The data‐independent acquisition mass spectrometry (DIA‐MS) has rapidly evolved as a
powerful alternative for highly reproducible proteome profiling with a unique strength of …

The eukaryotic cell is compartmentalized into subcellular niches, including membrane-
bound and membrane-less organelles. Proteins localize to these niches to fulfil their …

Current mass spectrometry methods enable high-throughput proteomics of large sample
amounts, but proteomics of low sample amounts remains limited in depth and throughput. To …

Mass spectrometry-based proteomics is constantly challenged by the presence of
contaminant background signals. In particular, protein contaminants from reagents and …

Single-cell methodologies and technologies have started a revolution in biology which until
recently has primarily been limited to deep sequencing and imaging modalities. With the …

Mass spectrometry is the driving force behind current brain proteome analysis. In a typical
proteomics approach, a protein isolate is digested into tryptic peptides and then analyzed by …

Thermal proteome profiling (TPP) provides a powerful approach to studying proteome-wide
interactions of small therapeutic molecules and their target and off-target proteins …

Rather than a “short‐term tenant,” the tumor microbiome has been shown to play a vital role
as a “permanent resident,” affecting carcinogenesis, cancer development, metastasis, and …

The evaluation of biopsied solid organ tissue has long relied on visual examination using a
microscope. Immunohistochemistry is critical in this process, labeling and detecting cell …

Background Fish and other aquatic foods (“blue foods”), possessing advantages of large
resources, species diversity, and high nutritional values, are becoming very important food …