Insights into the molecular alterations of PLAG1 and HMGA2 associated with malignant phenotype acquisition in pleomorphic adenoma
RA de Lima-Souza, G de Souza Vieira… - Critical Reviews in …, 2024 - Elsevier
Pleomorphic adenoma (PA) is the most common neoplasm of the salivary gland, presenting
with a variety of histological features. In some cases, PA can undergo malignant …
with a variety of histological features. In some cases, PA can undergo malignant …
Molecular landscape of salivary gland malignancies. What is already known?
J Pikul, A Rzepakowska - Contemporary Oncology/Współczesna …, 2024 - termedia.pl
Salivary gland carcinomas (SGCs) are highly heterogeneous histopathologi cal entities that
arise in either the ma jor or minor salivary glands. Although uncommon, these tumours …
arise in either the ma jor or minor salivary glands. Although uncommon, these tumours …
Molecular analysis using SalvGlandDx improves risk of malignancy estimation and diagnosis of salivary gland cytopathology: An exploratory multicenter study
SN Freiberger, K Ikenberg, D van Egmond… - Cancer …, 2024 - Wiley Online Library
Background Diagnosis of salivary gland neoplasms is challenging, especially on cytological
specimens acquired by fine‐needle aspiration. The recently implemented standardized …
specimens acquired by fine‐needle aspiration. The recently implemented standardized …
[HTML][HTML] Beneath HMGA2 alterations in pleomorphic adenomas: Pathological, immunohistochemical, and molecular insights
Aims Most salivary gland neoplasms are distinguished by specific recurrent gene fusions.
Recently, a subset of pleomorphic adenomas (PAs) originated from the parotid gland …
Recently, a subset of pleomorphic adenomas (PAs) originated from the parotid gland …
Fusions in salivary gland neoplasms: a review of practical diagnostic applications
JA Bishop - Journal of clinical pathology, 2024 - jcp.bmj.com
There is an ongoing explosion of new information regarding the underlying molecular
alterations driving a variety of salivary gland neoplasms. The volume of this emerging data …
alterations driving a variety of salivary gland neoplasms. The volume of this emerging data …
Peculiar nuclear atypia associated with MDM2 gene amplification in carcinoma ex‐pleomorphic adenoma harbouring an alteration of HMGA2
Z Alsugair, M Fieux, F Descotes, J Lopez… - …, 2024 - Wiley Online Library
Aims Salivary gland neoplasms (SGN) exhibiting the HMGA2:: WIF1 fusion are recognized
by their resemblance to histology found in canalicular adenoma. Recently,~ 20% of cases …
by their resemblance to histology found in canalicular adenoma. Recently,~ 20% of cases …
The Utility of BSND Immunohistochemistry in the Differential Diagnosis of Oncocytic and Warthin-like Mucoepidermoid Carcinoma of Salivary Gland
B Xu, A Jungbluth, D Frosina, A Alabkaa… - Head and Neck …, 2024 - Springer
Purpose BSND is a chloride channel subunit that is expressed in the normal salivary gland.
We aimed to validate the utility of BSND immunohistochemistry in the differential diagnosis …
We aimed to validate the utility of BSND immunohistochemistry in the differential diagnosis …
HMGA2‐positive salivary gland neoplasms with prominent trabecular/canalicular morphology: a focus on carcinomas arising within this phenotype
MN Dababneh, EM Azzato, J Nakitandwe… - …, 2025 - Wiley Online Library
Aims Pleomorphic adenoma (PA) with a prominent trabecular/canalicular morphology has
consistent HMGA2 protein expression, and association with HMGA2 fusions. We report our …
consistent HMGA2 protein expression, and association with HMGA2 fusions. We report our …
Les tumeurs des glandes salivaires associées à des transcrits de fusion
Résumé Les tumeurs des glandes salivaires représentent un défi diagnostique pour les
pathologistes en raison de leur rareté, de leur très grande variété histopathologique et …
pathologistes en raison de leur rareté, de leur très grande variété histopathologique et …
[HTML][HTML] Tumeurs des glandes salivaires: OMS 2022 et au-delà
C Lépine - Annales de Pathologie, 2024 - Elsevier
Résumé En 2022, la 5 e édition de la classification des tumeurs de la tête et du cou a été
publiée en ligne par l'OMS. Dans le chapitre des glandes salivaires, on trouve tout d'abord …
publiée en ligne par l'OMS. Dans le chapitre des glandes salivaires, on trouve tout d'abord …