Adult stem cells are fundamental to maintain tissue homeostasis, growth, and regeneration.
They reside in specialized environments called niches. Following activating signals, they …

The key hallmark of stem cells is their ability to self-renew while kee** a differentiation
potential. Intrinsic and extrinsic cell factors may contribute to a decline in these stem cell …

Although the adult mammalian heart is incapable of meaningful functional recovery
following substantial cardiomyocyte loss, it is now clear that modest cardiomyocyte turnover …

In the past decade, substantial evidence supports the paradigm that stem cells exert their
reparative and regenerative effects, in large part, through the release of biologically active …

The spectrum of ischaemic cardiomyopathy, encompassing acute myocardial infarction to
congestive heart failure is a significant clinical issue in the modern era. This group of …

Multipotent mesenchymal stromal/stem cells (MSCs) reside in many human organs and
comprise heterogeneous population of cells with self‐renewal ability. These cells can be …

Synthetically derived peptide-based biomaterials are in many instances capable of
mimicking the structure and function of their full-length endogenous counterparts. Combine …

Introduction This study was aimed at deciphering the secretome of adipose-derived
mesenchymal stromal cells (ADSCs) cultured in standard and hypoxic conditions to reveal …

Although transplantation of c-kit+ cardiac stem cells (CSCs) has been shown to alleviate left
ventricular (LV) dysfunction induced by myocardial infarction (MI), the number of exogenous …

The overall clinical cardiac regeneration experience suggests that stem cell therapy can be
safely performed, but it also underlines the need for reproducible results for their effective …