Biomedical features and therapeutic potential of rosmarinic acid

S Noor, T Mohammad, MA Rub, A Raza… - Archives of Pharmacal …, 2022 - Springer
For decades, the use of secondary metabolites of various herbs has been an attractive
strategy in combating human diseases. Rosmarinic acid (RA) is a bioactive phenolic …

Linking oxidative stress and proteinopathy in Alzheimer's disease

C Sharma, SR Kim - Antioxidants, 2021 - mdpi.com
Proteinopathy and excessive production of reactive oxygen species (ROS), which are the
principal features observed in the Alzheimer's disease (AD) brain, contribute to neuronal …

Natural compounds for Alzheimer's disease therapy: a systematic review of preclinical and clinical studies

S Andrade, MJ Ramalho, JA Loureiro… - International journal of …, 2019 - mdpi.com
Alzheimer's Disease (AD) is a neurodegenerative disorder related with the increase of age
and it is the main cause of dementia in the world. AD affects cognitive functions, such as …

Acetylcholinesterase inhibitors in the treatment of neurodegenerative diseases and the role of acetylcholinesterase in their pathogenesis

ŁJ Walczak-Nowicka, M Herbet - International journal of molecular …, 2021 - mdpi.com
Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

Natural polyphenols effects on protein aggregates in Alzheimer's and Parkinson's prion-like diseases

A Freyssin, G Page, B Fauconneau… - Neural regeneration …, 2018 - journals.lww.com
Alzheimer's and Parkinson's diseases are the most common neurodegenerative diseases.
They are characterized by protein aggregates and so can be considered as prion-like …

[HTML][HTML] Neuroprotective Benefits of Rosmarinus officinalis and Its Bioactives against Alzheimer's and Parkinson's Diseases

D Kosmopoulou, MP Lafara, T Adamantidi… - Applied Sciences, 2024 - mdpi.com
Featured Application Utilization of Rosmarinus officinalis extracts and/or its bioactives as
ingredients in functional products, foods, cosmetics, and pharmaceuticals, with anti …

Natural therapeutics in aid of treating alzheimer's disease: a green gateway toward ending quest for treating neurological disorders

BA Bhat, A Almilaibary, RA Mir, BM Aljarallah… - Frontiers in …, 2022 - frontiersin.org
The current scientific community is facing a daunting challenge to unravel reliable natural
compounds with realistic potential to treat neurological disorders such as Alzheimer's …

The role of dietary antioxidants in type 2 diabetes and neurodegenerative disorders: An assessment of the benefit profile

MT Fatima, AA Bhat, S Nisar, KA Fakhro, ASAS Akil - Heliyon, 2023 - cell.com
Healthy diet is vital to cellular health. The human body succumbs to numerous diseases
which afflict severe economic and psychological burdens on the patient and family …

Natural Anti-inflammatory compounds as Drug candidates in Alzheimer's disease

RH Mir, AJ Shah, R Mohi-Ud-Din… - Current medicinal …, 2021 - benthamdirect.com
Alzheimer's disease (AD) is a chronic neurodegenerative brain disorder characterized by
memory impairment, dementia, and oxidative stress in elderly people. Currently, only a few …

Molecular pharmacology of rosmarinic and salvianolic acids: Potential seeds for Alzheimer's and vascular dementia drugs

S Habtemariam - International Journal of Molecular Sciences, 2018 - mdpi.com
Both caffeic acid and 3, 4-dihydroxyphenyllactic acid (danshensu) are synthesized through
two distinct routs of the shikimic acid biosynthesis pathway. In many plants, especially the …