2, 5-DKP scaffolds are widely used in medicinal chemistry as the basis for many bioactive
compounds. These scaffolds have a wide range of biological properties, offering numerous …

Bis‐heterocycles were synthesized via a consecutive one‐pot process by a Groebke‐
Blackburn‐Bienaymé reaction (GBB‐3CR) followed by Copper‐catalyzed Alkyne‐Azide …

Multicomponent diversity–oriented synthesis (DOS) of conformationally anchored structural
peptidomimetics like 2, 5‐diketopiperazines (2, 5‐DKP) containing heterocyclic bioisosteres …

Various boron-containing isocyanides have been efficiently synthesized from the
corresponding enantiopure β-substituted β-amino boronic acid pinacol esters, without need …

2, 5-DKPs are heterocyclic peptidomimetics, present in nature with high structural diversity,
popular in the design of new bioactive molecules with potential application in medicinal …

2, 5-diketopiperazines (2, 5-DKPs) are the smallest cyclic peptides in nature and display a
variety of antibacterial, antifungal, and anticancer properties. Very little has been reported on …

Multicomponent reactions (MCR) are efficient and versatile modern synthetic tools, they also
have several advantages such as high convergence, operational simplicity, atomic …