Salivary biomarkers: novel noninvasive tools to diagnose chronic inflammation

P Dongiovanni, M Meroni, S Casati, R Goldoni… - International journal of …, 2023 - nature.com
Several chronic disorders including type 2 diabetes (T2D), obesity, heart disease and
cancer are preceded by a state of chronic low-grade inflammation. Biomarkers for the early …

Clinical significance of miRNAs in autoimmunity

L Zhang, H Wu, M Zhao, C Chang, Q Lu - Journal of autoimmunity, 2020 - Elsevier
MicroRNAs (miRNAs) are evolutionally conserved, single-stranded RNAs that regulate gene
expression at the posttranscriptional level by disrupting translation. MiRNAs are key players …

Circulating microRNAs as potential diagnostic and prognostic biomarkers in hepatocellular carcinoma

Y **, YS Wong, BKP Goh, CY Chan, PC Cheow… - Scientific Reports, 2019 - nature.com
Hepatocellular carcinoma (HCC) is the fifth most common cancer with high mortality, due to
late diagnosis and limited treatment options. Blood miRNAs, which circulate in a highly …

Salivary microRNA for diagnosis of cancer and systemic diseases: a systematic review

G Setti, ME Pezzi, MV Viani, TA Pertinhez… - International journal of …, 2020 - mdpi.com
Background: The aberrant expression of microRNAs (miRNAs) has been associated with
several diseases, including cancer, inflammatory, and autoimmune conditions. Interest in …

The liquid biopsy in the management of colorectal cancer: an overview

M Vacante, R Ciuni, F Basile, A Biondi - Biomedicines, 2020 - mdpi.com
Currently, there is a crucial need for novel diagnostic and prognostic biomarkers with high
specificity and sensitivity in patients with colorectal cancer. A “liquid biopsy” is characterized …

Salivary small extracellular vesicles associated miRNAs in periodontal status—A pilot study

P Han, PM Bartold, C Salomon, S Ivanovski - International journal of …, 2020 - mdpi.com
This pilot study aims to investigate whether salivary small extracellular vesicle (sEV)-
associated microRNAs could act as potential biomarkers for periodontal disease status …

Cell-free miRNAs as non-invasive biomarkers in breast cancer: Significance in early diagnosis and metastasis prediction

D Kashyap, H Kaur - Life sciences, 2020 - Elsevier
Breast cancer is one of the genetic diseases causing a high mortality among women around
the world. Despite the availability of advanced diagnostic tools and treatment strategies, the …

A novel saliva-based miRNA signature for colorectal cancer diagnosis

Ó Rapado-González, B Majem… - Journal of clinical …, 2019 - mdpi.com
Salivary microRNAs (miRNAs) are of high interest as diagnostic biomarkers for non-oral
cancer. However, little is known about their value for colorectal cancer (CRC) detection. Our …