Health beneficial and pharmacological properties of p-cymene

A Balahbib, N El Omari, NEL Hachlafi, F Lakhdar… - Food and Chemical …, 2021 - Elsevier
Abstract p-cymene also known as p-cymol or p-isopropyltoluene is an alkyl-substituted
aromatic compound naturally occurring in essential oils (EOs) of various aromatic plants …

Platinum, palladium, gold and ruthenium complexes as anticancer agents: Current clinical uses, cytotoxicity studies and future perspectives

T Lazarević, A Rilak, ŽD Bugarčić - European journal of medicinal chemistry, 2017 - Elsevier
Metallodrugs offer potential for unique mechanism of drug action based on the choice of the
metal, its oxidation state, the types and number of coordinated ligands and the coordination …

The development of RAPTA compounds for the treatment of tumors

BS Murray, MV Babak, CG Hartinger… - Coordination Chemistry …, 2016 - Elsevier
Abstract Ruthenium (II)-arene RAPTA-type compounds have been extensively explored for
their medicinal properties. Herein a comprehensive review of this class of compounds is …

Ruthenium complexes as antimicrobial agents

F Li, JG Collins, FR Keene - Chemical Society Reviews, 2015 - pubs.rsc.org
One of the major advances in medical science has been the development of antimicrobials;
however, a consequence of their widespread use has been the emergence of drug-resistant …

Chemistry and reactivity of ruthenium (II) complexes: DNA/protein binding mode and anticancer activity are related to the complex structure

AR Simović, R Masnikosa, I Bratsos… - Coordination Chemistry …, 2019 - Elsevier
In this review we summarize our work on development of Ru complexes with potential
antitumor activity, which was performed over the last few years. In order to establish the …

Bioorganometallic chemistry—from teaching paradigms to medicinal applications

CG Hartinger, PJ Dyson - Chemical Society Reviews, 2009 - pubs.rsc.org
In undergraduate level organometallic chemistry courses students are usually taught that
organometallic compounds are toxic and unstable in air and water. While this is true of many …

Arene ruthenium complexes as anticancer agents

G Süss-Fink - Dalton Transactions, 2010 - pubs.rsc.org
Neutral or cationic arene ruthenium complexes providing both hydrophilic as well as
hydrophobic properties due to the robustness of the ruthenium–arene unit hold a high …

In vitro and in vivo evaluation of ruthenium (II)− arene PTA complexes

C Scolaro, A Bergamo, L Brescacin… - Journal of medicinal …, 2005 - ACS Publications
The antitumor activity of the organometallic ruthenium (II)− arene complexes, RuCl2 (η6-
arene)(PTA),(arene= p-cymene, toluene, benzene, benzo-15-crown-5, 1-ethylbenzene-2, 3 …

An overview of advancement of organoruthenium (II) complexes as prospective anticancer agents

M Bashir, IA Mantoo, F Arjmand, S Tabassum… - Coordination Chemistry …, 2023 - Elsevier
The successful clinical translation of platinum drugs for cancer treatment has witnessed an
upsurge in the development of metal compounds as therapeutics and diagnostics drugs …

Classical and non‐classical ruthenium‐based anticancer drugs: Towards targeted chemotherapy

W Han Ang, PJ Dyson - European Journal of Inorganic …, 2006 - Wiley Online Library
Ruthenium‐based anticancer chemotherapies are making significant advances in clinical
trials. Until recently, the focus has been on coordination complexes, and mechanisms such …