Esophageal cancer is a deadly disease, ranking sixth among all cancers in mortality.
Despite incremental advances in diagnostics and therapeutics, esophageal cancer still …

Although inflammation has long been known as a localized protective reaction of tissue to
irritation, injury, or infection, characterized by pain, redness, swelling, and sometimes loss of …

Numerous experimental, epidemiologic, and clinical studies suggest that nonsteroidal anti-
inflammatory drugs (NSAIDs), particularly the highly selective cyclooxygenase (COX)-2 …

The aim of evidence-based medicine is to improve the quality of health care by integrating
the best research evidence with clinical expertise and patient values. Evidence-based …

Importance Barrett esophagus, a complication of gastroesophageal reflux disease (GERD),
predisposes patients to esophageal adenocarcinoma, a tumor that has increased in …

Increasing evidence from epidemiological, preclinical and clinical studies suggests that
dysregulated inflammatory response plays a pivotal role in a multitude of chronic ailments …

We comprehensively reviewed the published scientific literature on non-steroidal anti-
inflammatory drugs (NSAIDs) and cancer and evaluated results based upon epidemiologic …

Background & Aims: The diagnosis and management of Barrett's esophagus (BE) are
controversial. We conducted a critical review of the literature in BE to provide guidance on …

Abstract Cyclooxygenase‐2 (COX‐2) is the inducible isoform of cyclooxygenase, the
enzyme that catalyzes the rate‐limiting step in prostaglandin synthesis from arachidonic …

Esophageal cancer (EC) is frequently considered a lethal malignancy and is often identified
at a later stage. It is one of the major causes of cancer-related deaths globally. The …