The vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) play crucial
roles in vasculogenesis and angiogenesis. Angiogenesis is an important mechanism in …

Simple Summary Tumors are not masses of cancer cells alone but made up of cancer cells,
other cells including fibroblasts, macrophages, endothelial cells, as well as secreted factors …

Distant metastasis is a primary cause of mortality and contributes to poor surgical outcomes
in cancer patients. Before the development of organ-specific metastasis, the formation of a …

Abstract Though Forkhead box P (FOXP) transcription factors comprising of FOXP1, FOXP2,
FOXP3 and FOXP4 are involved in the embryonic development, immune disorders and …

The acquired ability to induce the formation of a functional vasculature is a hallmark of
cancer. Blood vessels in tumors are formed through various mechanisms, among the most …

Hydroxytyrosol (HT) is a phenolic compound with proven biological properties present in a
limited number of foods such as table olives, virgin olive oil (VOO) and wines. The present …

Simple Summary With 19.3 million new cancer cases worldwide and nearly 10.0 million
cancer-related deaths cancer is a global health challenge. Cancer is a disease caused by a …

Background Spindle and kinetochore-associated complex subunit 3 (SKA3) plays an
important role in cell proliferation by regulating the separation of chromosomes and their …

Cancer is a heterogeneous and multifactorial disease that causes high mortality throughout
the world; therefore, finding the most effective therapies is a major research challenge …

Somatostatin (SST), a growth hormone inhibitory peptide, is expressed in endocrine and
non-endocrine tissues, immune cells and the central nervous system (CNS). Post-release …