Similarly to our healthy organs, the tumor tissue also constitutes an ecosystem. This implies
that stromal cells acquire an altered phenotype in tandem with tumor cells, thereby …

Immune checkpoint molecules are a group of molecules expressed on the surface of
immune cells that primarily regulate their immune homeostasis. Chimeric antigen receptor …

An immune checkpoint is a signaling pathway that regulates the recognition of antigens by T-
cell receptors (TCRs) during an immune response. These checkpoints play a pivotal role in …

This review explores the hallmarks of cancer resistance, including drug efflux mediated by
ATP-binding cassette (ABC) transporters, metabolic reprogramming characterized by the …

Phenylboronic acid (PBA) is recognized as one of the most promising cancer cell binding
modules attributed to its potential to form reversible and dynamic boronic ester covalent …

Introduction: An increasing number of immune-related adverse events (irAEs) induced by
immune checkpoint inhibitors (ICIs) have been reported during clinical treatment. We aimed …

Advancing personalized medicine in brain cancer relies on innovative strategies, with
mRNA vaccines emerging as a promising avenue. While the initial use of mRNA vaccines …

Immune checkpoint inhibitors (ICIs) have revolutionized the field of anti-cancer therapy over
the last decade; they provide durable clinical responses against tumors by inhibiting …

In addition to conventional chemoradiation and targeted cancer therapy, the use of immune
based therapies, specifically immune checkpoint inhibitors (ICIs) and chimeric antigen …

This study explores the impact of antiretroviral administration on the expression of human
endogenous retroviruses (HERVs), cell growth, and invasive capability of human melanoma …