Oxidative stress is a critical factor in the pathogenesis and progression of diabetes and its
associated complications. The imbalance between reactive oxygen species (ROS) …

Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) family (PGC-1s),
consisting of three members encompassing PGC-1α, PGC-1β, and PGC-1-related …

The silent information regulator sirtuin 1 (SIRT1) protein, a highly conserved NAD+-
dependent deacetylase belonging to the sirtuin family, is a post-translational regulator that …

Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Nonalcoholic fatty liver disease (NAFLD), recently renamed metabolic-associated fatty liver
disease (MAFLD), is one of the most common causes of liver diseases worldwide. NAFLD is …

The goal of a biomaterial is to support the bone tissue regeneration process at the defect site
and eventually degrade in situ and get replaced with the newly generated bone tissue …

Poultry in commercial settings are exposed to a range of stressors. A growing body of
information clearly indicates that excess ROS/RNS production and oxidative stress are …

Sirtuin 3 (SIRT3) is one of the most prominent deacetylases that can regulate acetylation
levels in mitochondria, which are essential for eukaryotic life and inextricably linked to the …

The kidney requires a large number of mitochondria to remove waste from the blood and
regulate fluid and electrolyte balance. Mitochondria provide the energy to drive these …

Silent information regulator 1 (SIRT1), a highly conserved NAD+-dependent deacetylase, is
a cellular regulator that has received extensive attention in recent years and regarded as a …