Natural isoquinoline alkaloids: Pharmacological features and multi-target potential for complex diseases
Complex diseases such as neurodegenerative disorders and cancer constitute a growing
public health problem due to the rising incidence and lack in effective therapies. Since …
public health problem due to the rising incidence and lack in effective therapies. Since …
Heroin and its metabolites: relevance to heroin use disorder
Heroin is an opioid agonist commonly abused for its rewarding effects. Since its synthesis at
the end of the nineteenth century, its popularity as a recreational drug has ebbed and …
the end of the nineteenth century, its popularity as a recreational drug has ebbed and …
Structural diversity, evolutionary origin, and metabolic engineering of plant specialized benzylisoquinoline alkaloids
Y Tian, L Kong, Q Li, Y Wang, Y Wang, Z An… - Natural product …, 2024 - pubs.rsc.org
Covering: up to June 2024 Benzylisoquinoline alkaloids (BIAs) represent a diverse class of
plant specialized metabolites derived from L-tyrosine, exhibiting significant pharmacological …
plant specialized metabolites derived from L-tyrosine, exhibiting significant pharmacological …
Multiproxy study of 7500-year-old wooden sickles from the Lakeshore Village of La Marmotta, Italy
The lakeshore site of La Marmotta is one of the most important Early Neolithic sites of
Mediterranean Europe. The site is famous for the exceptional preservation of organic …
Mediterranean Europe. The site is famous for the exceptional preservation of organic …
Insights into opium poppy (Papaver spp.) genetic diversity from genoty**-by-sequencing analysis
Opium poppy (Papaver somniferum) is one of the world's oldest medicinal plants and a
versatile model system to study secondary metabolism. However, our knowledge of its …
versatile model system to study secondary metabolism. However, our knowledge of its …
Genomic and cell-specific regulation of benzylisoquinoline alkaloid biosynthesis in opium poppy
Opium poppy is a crop of great commercial value as a source of several opium alkaloids for
the pharmaceutical industries including morphine, codeine, thebaine, noscapine, and …
the pharmaceutical industries including morphine, codeine, thebaine, noscapine, and …
Direct evidence of the use of multiple drugs in Bronze Age Menorca (Western Mediterranean) from human hair analysis
Human hair dated to Late Prehistory is exceedingly rare in the Western Mediterranean.
Archaeological excavations in the Bronze Age burial and cult cave of Es Càrritx, in Menorca …
Archaeological excavations in the Bronze Age burial and cult cave of Es Càrritx, in Menorca …
A morphometric approach to track opium poppy domestication
Opium poppy (Papaver somniferum L. subsp. somniferum) was likely domesticated in the
Western Mediterranean, where its putative wild ancestor is indigenous, and then spread to …
Western Mediterranean, where its putative wild ancestor is indigenous, and then spread to …
A revised tribal classification of Papaveraceae (poppy family) based on molecular and morphological data
HW Peng, KL **ang, L Lian, B Liu, AS Erst, TG Gao… - Taxon, 2024 - Wiley Online Library
Papaveraceae, commonly known as the poppy family, contains many species with
horticultural and/or pharmaceutical importance and has been the subject of various …
horticultural and/or pharmaceutical importance and has been the subject of various …
A cornucopia of diversity—Ranunculales as a model lineage
The Ranunculales are a hyperdiverse lineage in many aspects of their phenotype, including
growth habit, floral and leaf morphology, reproductive mode, and specialized metabolism …
growth habit, floral and leaf morphology, reproductive mode, and specialized metabolism …