Computational identification of disease models through cross-species phenotype comparison

P Cacheiro, D Pava, H Parkinson… - Disease Models & …, 2024‏ - journals.biologists.com
The use of standardised phenoty** screens to identify abnormal phenotypes in mouse
knockouts, together with the use of ontologies to describe such phenotypic features, allows …

A review of standardized high-throughput cardiovascular phenoty** with a link to metabolism in mice

J Lindovsky, Z Nichtova, NRV Dragano… - Mammalian …, 2023‏ - Springer
Cardiovascular diseases cause a high mortality rate worldwide and represent a major
burden for health care systems. Experimental rodent models play a central role in …

[HTML][HTML] In Vitro Models of Cardiovascular Disease: Embryoid Bodies, Organoids and Everything in Between

TM Stougiannou, KC Christodoulou… - Biomedicines, 2024‏ - pmc.ncbi.nlm.nih.gov
Cardiovascular disease comprises a group of disorders affecting or originating within tissues
and organs of the cardiovascular system; most, if not all, will eventually result in …

Elevated IGFBP7 expression in follicular granulosa cells promotes PCOS pathogenesis

L Chen, L Hui, Y Wang, X Yao, J Li - Biochimica et Biophysica Acta (BBA) …, 2025‏ - Elsevier
Polycystic ovary syndrome (PCOS) can result in female infertility, menstrual irregularities,
metabolic disturbances, hormonal imbalances, and significantly impact the reproductive …

Mouse Cardiovascular Imaging

CKL Phoon, O Aristizábal, M Farhoud… - Current …, 2024‏ - Wiley Online Library
The mouse is the mammalian model of choice for investigating cardiovascular biology, given
our ability to manipulate it by genetic, pharmacologic, mechanical, and environmental …

From mechanisms of heart failure to clinical heart success

J Bakkers, M Bellin, J Hmeljak… - Disease Models & …, 2023‏ - journals.biologists.com
Heart failure is characterised by the heart's inability to pump blood effectively, leading to
reduced oxygen and nutrient supply to the body's organs and tissues, and is the leading …

[PDF][PDF] PHENOTYPE OF GENETIC KNOCKOUT STRAINS IN DIMETHYLBENZ (A) ANTHRACENE AND 12-O-TETRADECANOYL PHORBOL-13-ACETATE (DMBA …

M Hyttinen, T Komulainen, T Järvinen - 2024‏ - researchgate.net
Experimental two-stage skin cancer model induced by dimethylbenz (a) anthracene (DMBA)
and 12-O-tetradecanoyl phorbol-13-acetate (TPA) is an ideal model for exploring individual …

SHJH hr 小鼠的心脏衰老表型研究

刘荣乐, 程灏, 尚付生, 常书福, 徐** - 实验动物与比较医学, 2025‏ - slarc.org.cn
目的探讨自发性早衰小鼠(SHJH hr 小鼠) 心脏的衰老现象. 方法对不同周龄(10 周龄和24 周龄)
的SHJH hr 小鼠(SHJH hr 组) 和ICR 小鼠(野生型组即WT 组) 进行对比研究 …