Can the natural diversity of quorum-sensing advance synthetic biology?

RM Davis, RY Muller, KA Haynes - Frontiers in bioengineering and …, 2015 - frontiersin.org
Quorum-sensing networks enable bacteria to sense and respond to chemical signals
produced by neighboring bacteria. They are widespread: over 100 morphologically and …

Potential role of probiotics in reducing Clostridioides difficile virulence: Interference with quorum sensing systems

S Gunaratnam, M Millette, LV McFarland… - Microbial …, 2021 - Elsevier
Opportunistic pathogenic bacteria may cause disease after the normally protective
microbiome is disrupted (typically by antibiotic exposure). Clostridioides difficile is one such …

Phenotypic memory in quorum sensing

G Ostovar, JQ Boedicker - PLoS Computational Biology, 2024 - journals.plos.org
Quorum sensing (QS) is a regulatory mechanism used by bacteria to coordinate group
behavior in response to high cell densities. During QS, cells monitor the concentration of …

Macroscopic quorum sensing sustains differentiating embryonic stem cells

H Daneshpour, P Van den Bersselaar… - Nature chemical …, 2023 - nature.com
Cells can secrete molecules that help each other's replication. In cell cultures, chemical
signals might diffuse only within a cell colony or between colonies. A chemical signal's …

Integration of metabolic and quorum sensing signals governing the decision to cooperate in a bacterial social trait

KE Boyle, H Monaco, D van Ditmarsch… - PLoS computational …, 2015 - journals.plos.org
Many unicellular organisms live in multicellular communities that rely on cooperation
between cells. However, cooperative traits are vulnerable to exploitation by non-cooperators …

[HTML][HTML] Molecular-level tuning of cellular autonomy controls the collective behaviors of cell populations

T Maire, H Youk - Cell systems, 2015 - cell.com
A rigorous understanding of how multicellular behaviors arise from the actions of single cells
requires quantitative frameworks that bridge the gap between genetic circuits, the …

Cooperative growth in microbial communities is a driver of multistability

W Lopes, DR Amor, J Gore - Nature Communications, 2024 - nature.com
Microbial communities often exhibit more than one possible stable composition for the same
set of external conditions. In the human microbiome, these persistent changes in species …

An Engineered Device for Indoleacetic Acid Production under Quorum Sensing Signals Enables Cupriavidus pinatubonensis JMP134 To Stimulate Plant Growth

A Zúñiga, F Fuente, F Federici, C Lionne… - ACS Synthetic …, 2018 - ACS Publications
The environmental effects of chemical fertilizers and pesticides have encouraged the quest
for new strategies to increase crop productivity with minimal impacts on the natural medium …

Microbial communication via quorum sensing

J Boedicker, K Nealson - IEEE Transactions on Molecular …, 2015 - ieeexplore.ieee.org
Chemical communication enables microbes to probe local cell density and coordinate
collective behavior through a process known as quorum sensing (QS). In QS, microbes …

Queuing models for abstracting interactions in bacterial communities

N Michelusi, J Boedicker… - IEEE Journal on …, 2016 - ieeexplore.ieee.org
Microbial communities play a significant role in bioremediation, plant growth, human and
animal digestion, global elemental cycles including the carbon-cycle, and water treatment …