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Biomarkers of oxidative stress and antioxidant defense
A number of reactive oxygen and nitrogen species are produced during normal metabolism
in human body. These species can be both radical and non-radical and have varying …
in human body. These species can be both radical and non-radical and have varying …
Unlocking the potential of mesoporous silica nanoparticles in breast cancer treatment
Breast cancer is the most common cancer among women and is typically managed through
surgery, radiation therapy, and chemotherapy. However, chemotherapy drugs often lack …
surgery, radiation therapy, and chemotherapy. However, chemotherapy drugs often lack …
Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence
Cancer recurrence after initial diagnosis and treatment is a major cause of breast cancer
(BC) mortality, which results from the metastatic outbreak of dormant tumour cells …
(BC) mortality, which results from the metastatic outbreak of dormant tumour cells …
Role and mechanisms of mitophagy in liver diseases
The mitochondrion is an organelle that plays a vital role in the regulation of hepatic cellular
redox, lipid metabolism, and cell death. Mitochondrial dysfunction is associated with both …
redox, lipid metabolism, and cell death. Mitochondrial dysfunction is associated with both …
Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines
Breast cancer is one of the leading causes of mortality among women worldwide due to
aggressive behavior, early metastasis, resistance to existing chemotherapeutic agent and …
aggressive behavior, early metastasis, resistance to existing chemotherapeutic agent and …
[HTML][HTML] The fate of chemoresistance in triple negative breast cancer (TNBC)
EA O'Reilly, L Gubbins, S Sharma, R Tully, MHZ Guang… - BBA clinical, 2015 - Elsevier
Background Treatment options for women presenting with triple negative breast cancer
(TNBC) are limited due to the lack of a therapeutic target and as a result, are managed with …
(TNBC) are limited due to the lack of a therapeutic target and as a result, are managed with …
Excess TGF-β mediates muscle weakness associated with bone metastases in mice
Cancer-associated muscle weakness is a poorly understood phenomenon, and there is no
effective treatment. Here we find that seven different mouse models of human osteolytic …
effective treatment. Here we find that seven different mouse models of human osteolytic …
Carbohydrate polymer-based nanocomposites for breast cancer treatment
Breast cancer is known as the most common invasive malignancy in women with the highest
mortality rate worldwide. This concerning disease may be presented in situ (relatively easier …
mortality rate worldwide. This concerning disease may be presented in situ (relatively easier …
[HTML][HTML] Triple negative breast cancer: a mountain yet to be scaled despite the triumphs
Simple Summary Triple-negative breast cancer (TNBC) is a highly aggressive subtype of
breast cancer that cannot be treated with endocrine therapy and Her2-targeted therapy …
breast cancer that cannot be treated with endocrine therapy and Her2-targeted therapy …
Reactive oxygen and nitrogen species in carcinogenesis: implications of oxidative stress on the progression and development of several cancer types
Background: The body of evidence available from published literature during the past three
decades indicates that reactive oxygen species and reactive nitrogen species can induce …
decades indicates that reactive oxygen species and reactive nitrogen species can induce …