Pyroptosis is a type of programmed cell death characterized by cell swelling and osmotic
lysis, resulting in cytomembrane rupture and release of immunostimulatory components …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) characterized by demyelination. Current treatment options for MS focus on …

Objective This study aimed to investigate the regulatory role of astrocyte-derived exosomes
and their microRNAs (miRNAs) in modulating neuronal pyroptosis during cerebral ischemia …

Copper, a vital mineral nutrient, possesses redox qualities that make it both beneficial and
toxic to organisms. Excessive environmental copper exposure can result in neurological …

Pyroptosis is an inflammatory form of programmed cell death that is distinct from necrosis
and apoptosis. Pyroptosis is primarily mediated by the gasdermin family of proteins (GSDMA …

Methamphetamine is a widely abused drug associated with significant neuroinflammation
and neurodegeneration, mainly through the activation of glial cells and neurons in the …

Cell death is a central process for organismal health. Pyroptosis, namely pyroptotic cell
death, is recognized as a critical type that disrupts membrane and triggers pro-inflammatory …

Pulmonary arterial hypertension (PAH) is a severe cardiovascular disease characterized by
elevated pulmonary vascular resistance, progressive increases in pulmonary artery …

Neuroinflammation is a major driver of postoperative cognitive dysfunction (POCD). The
cyclic GMP-AMP synthase-stimulator of interferon gene (cGAS–STING) signaling is a …

HERVs (Human endogenous retroviruses) are remnants of ancient exogenous retroviruses
that have integrated into the human genome, particularly in germ-line cells. Among these …