Saturated five-membered thiazolidines and their derivatives: from synthesis to biological applications
In past decades, interdisciplinary research has been of great interest for scholars.
Thiazolidine motifs behave as a bridge between organic synthesis and medicinal chemistry …
Thiazolidine motifs behave as a bridge between organic synthesis and medicinal chemistry …
Synthesis, DFT studies, molecular docking and biological activity evaluation of thiazole-sulfonamide derivatives as potent Alzheimer's inhibitors
Alzheimer's disease is a major public brain condition that has resulted in many deaths, as
revealed by the World Health Organization (WHO). Conventional Alzheimer's treatments …
revealed by the World Health Organization (WHO). Conventional Alzheimer's treatments …
Synthesis, in vitro α-amylase, α-glucosidase activities and molecular docking study of new benzimidazole bearing thiazolidinone derivatives
We have synthesized a series of benzimidazole bearing thiazolidinone derivatives (1-20),
characterized through NMR and HREI-MS and screened against α-glucosidase and α …
characterized through NMR and HREI-MS and screened against α-glucosidase and α …
[HTML][HTML] Synthesis, biological evaluation and molecular docking study of pyrimidine based thiazolidinone derivatives as potential anti-urease and anti-cancer agents
Hybrid analogs containing molecules are always the choice of different synthetic researcher
due to their diverse biological applications and significantly more efficient. Heterocyclic …
due to their diverse biological applications and significantly more efficient. Heterocyclic …
Synthesis of new carboxylates and sulfonates containing thiazolidin-4-one ring and evaluation of inhibitory properties against some metabolic enzymes
A series of thizaolidin-4-one derivatives (3a-o) was synthesized with excellent yield (94–
97%) and the structures of the compounds were characterized with Fourier-transform …
97%) and the structures of the compounds were characterized with Fourier-transform …
New thiazole-based thiazolidinone derivatives: synthesis, in vitro α-amylase, α-glucosidase activities and silico molecular docking study
A series of thiazole-based thiazolidinone derivatives (1-20) have been synthesized and
evaluated against α-glucosidase and α-amylase enzymes. All derivatives showed good α …
evaluated against α-glucosidase and α-amylase enzymes. All derivatives showed good α …
Thiadiazole based triazole/hydrazone derivatives: Synthesis, in vitro α-glucosidase inhibitory activity and in silico molecular docking study
Thiadiazole-based hydrazide was treated with different substituted phenyl isothiocyanates
and benzaldehyde to synthesize thiadiazole-based triazole/hydrazone derivatives (4a–h & …
and benzaldehyde to synthesize thiadiazole-based triazole/hydrazone derivatives (4a–h & …
Urease Inhibition and Structure‐Activity Relationship Study of Thiazolidinone‐, Triazole‐, and Benzothiazole‐Based Heterocyclic Derivatives: A Focus Review
Urease has a long and distinguished history in the development of enzymology since it was
the first enzyme crystallized by Sumner in 1926. The present review article is focused on the …
the first enzyme crystallized by Sumner in 1926. The present review article is focused on the …
[1, 2, 4] triazolo [3, 4-b][1, 3, 4] thiadiazole derivatives as new therapeutic candidates against urease positive microorganisms: design, synthesis, pharmacological …
M Khalili Ghomi, M Noori, M Nazari Montazer… - Scientific Reports, 2023 - nature.com
Regarding the important role of the urease enzyme as a virulence factor in urease-positive
microorganisms in this study, new series of [1, 2, 4] triazolo [3, 4-b][1, 3, 4] thiadiazole …
microorganisms in this study, new series of [1, 2, 4] triazolo [3, 4-b][1, 3, 4] thiadiazole …
In vitro α-glucosidase and α-amylase inhibitory potential and molecular docking studies of benzohydrazide based imines and thiazolidine-4-one derivatives
Benzohydrazide based imine derivatives (1c-16c) and thiazolidine-4-one derivatives (1d-
16d) were synthesized and characterized with different spectroscopic techniques ie HREI …
16d) were synthesized and characterized with different spectroscopic techniques ie HREI …