Type 2 diabetes mellitus (T2DM) is an expanding global health problem, closely linked to
the epidemic of obesity. Individuals with T2DM are at high risk for both microvascular …

There are different types of nutritionally mediated oxidative stress sources that trigger
inflammation. Much information indicates that high intakes of macronutrients can promote …

Obesity, a social problem worldwide, is characterized by an increase in body weight that
results in excessive fat accumulation. Obesity is a major cause of morbidity and mortality and …

Mitochondria play a key role in maintaining energy homeostasis in metabolic tissues,
including adipose tissues. The two main types of adipose tissues are the white adipose …

Adipose tissue is now recognized as an important endocrine organ, capable of secreting a
large number of endocrine factors which regulate a wide variety of physiological functions …

Mitochondria play a key role in energy metabolism in many tissues, including cardiac and
skeletal muscle, brain, liver, and adipose tissue. Three types of adipose depots can be …

Oxidative stress plays a pathological role in the development of various diseases including
diabetes, atherosclerosis, or cancer. Systemic oxidative stress results from an imbalance …

Background Insulin resistance not only occurs in obesity, but also in lipodystrophy. Although
adipose tissue mass affects metabolic fluxes and participates in interorgan crosstalk, the role …

White adipose tissue is one of the largest organs of the body. It plays a key role in whole‐
body energy status and metabolism; it not only stores excess energy but also secretes …

Insulin resistance and obesity are associated with a reduction of mitochondrial content in
various tissues of mammals. Moreover, a reduced nitric oxide (NO) bioavailability impairs …