After conquering the atomic structure about a century ago, chemists have been largely
interested in understanding the concept of chemical bond and the formation of a molecule …

Noncovalent interactions are essential for the existence of solid and liquid phases. 1, 2
Traditionally touted as weak forces, quantification of these interactions, which govern the …

Cation–π interactions are common in nature, especially in organisms. Their profound
influences in chemistry, physics, and biology have been continuously investigated since …

Nanomedicine is a discipline that applies nanoscience and nanotechnology principles to the
prevention, diagnosis, and treatment of human diseases. Self-assembly of molecular …

Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

Piezo proteins are transmembrane ion channels which transduce many forms of mechanical
stimuli into electrochemical signals. Their pore, formed by the assembly of three identical …

Voltage-gated proton channels (HV) are unique, in part because the ion they conduct is
unique. HV channels are perfectly selective for protons and have a very small unitary …

An understanding of the nervous system at virtually any level of analysis requires an
understanding of its basic building block, the neuron. The third edition of From Molecules to …

We celebrate this year the 50th anniversary of the first electrophysiological recordings of the
gating currents from voltage-dependent ion channels done in 1973. This retrospective tries …

Hv1 voltage-gated proton channels mediate rapid and selective transmembrane H+ flux and
are gated by both voltage and pH gradients. Selective H+ transfer in membrane proteins is …