Currently, chemotherapy is the main treatment for tumors, but there are still problems such
as unsatisfactory chemotherapy results, susceptibility to drug resistance, and serious …

The genotoxic methylating agents temozolomide (TMZ) and procarbazine and the
chloroethylating nitrosourea lomustine (CCNU) are part of the standard repertoire in the …

Simple Summary This review offers a thorough examination of the potential role and
structural properties of MGMT, the progression in targeting MGMT, and the interactions …

Temozolomide (TMZ) is a methylating agent used as the first-line drug in the chemotherapy
of glioblastomas. However, cancer cells eventually acquire resistance, necessitating the …

Background: Glioblastoma (GBM) is the most aggressive and lethal central nervous system
(CNS) tumor. The treatment strategy is mainly surgery and/or radiation therapy, both …

Background Temozolomide (TMZ) resistance is the main obstacle faced by glioblastoma
multiforme (GBM) treatment. Muscone, one of the primary active pharmacological …

Background There has been no research investigating susceptibility-weighted imaging
(SWI) radiomics features in evaluating molecular makers in gliomas. The aim of this study …

Neuroendocrine tumors (NETs) are a diverse group of tumors that arise from
neuroendocrine cells and are commonly found in various organs. A considerable proportion …

Purpose To assess the predictive value of radiomics features extracted from structural MRI,
dynamic contrast enhanced (DCE), and diffusion tensor imaging (DTI) in detecting O6 …

Simple Summary Mutation of the SMARCB1 gene can cause one of the most aggressive
and lethal cancers of early childhood and infancy, malignant rhabdoid tumor (MRT). Despite …