Lipid-based nanoparticle technologies for liver targeting
Liver diseases such as hepatitis, cirrhosis, and hepatocellular carcinoma are global health
problems accounting for approximately 800 million cases and over 2 million deaths per year …
problems accounting for approximately 800 million cases and over 2 million deaths per year …
Development and characterization of the solvent-assisted active loading technology (SALT) for liposomal loading of poorly water-soluble compounds
A large proportion of pharmaceutical compounds exhibit poor water solubility, impacting
their delivery. These compounds can be passively encapsulated in the lipid bilayer of …
their delivery. These compounds can be passively encapsulated in the lipid bilayer of …
[HTML][HTML] Nuclear MYH9-induced CTNNB1 transcription, targeted by staurosporin, promotes gastric cancer cell anoikis resistance and metastasis
G Ye, Q Yang, X Lei, X Zhu, F Li, J He, H Chen… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Peritoneal metastasis predicts poor prognosis of gastric cancer (GC) patients,
and the underlying mechanisms are poorly understood. Methods: The 2-DIGE, MALDI …
and the underlying mechanisms are poorly understood. Methods: The 2-DIGE, MALDI …
DOX/ICG coencapsulated liposome-coated thermosensitive nanogels for NIR-triggered simultaneous drug release and photothermal effect
L Yu, A Dong, R Guo, M Yang, L Deng… - … Biomaterials Science & …, 2018 - ACS Publications
Chemo-photothermal therapy has shown enormous potential in treating cancer. To achieve
the chemo-photothermal synergistic effect, an efficient nanoparticulate system with the ability …
the chemo-photothermal synergistic effect, an efficient nanoparticulate system with the ability …
Liposome-based probes for molecular imaging: from basic research to the bedside
Molecular imaging is very important in disease diagnosis and prognosis. Liposomes are
excellent carriers for different types of molecular imaging probes. In this work, we summarize …
excellent carriers for different types of molecular imaging probes. In this work, we summarize …
Development of thermosensitive resiquimod-loaded liposomes for enhanced cancer immunotherapy
Resiquimod (R848) is a toll-like receptor 7 and 8 (TLR7/8) agonist with potent antitumor and
immunostimulatory activity. However, systemic delivery of R848 is poorly tolerated because …
immunostimulatory activity. However, systemic delivery of R848 is poorly tolerated because …
Recent advances in applying nanotechnologies for cancer immunotherapy
Cancer immunotherapy aimed at boosting cancer-specific immunoresponses to eradicate
tumor cells has evolved as a new treatment modality. Nanoparticles incorporating antigens …
tumor cells has evolved as a new treatment modality. Nanoparticles incorporating antigens …
Systemic study of solvent-assisted active loading of gambogic acid into liposomes and its formulation optimization for improved delivery
The solvent-assisted active loading technology (SALT) was developed for encapsulating a
water insoluble weak base into the liposomal core in the presence of 5% DMSO. In this …
water insoluble weak base into the liposomal core in the presence of 5% DMSO. In this …
Cancer theranostic applications of lipid-based nanoparticles
Highlights•LNPs can be doped with multiple components for theranostics.•LNPs allow
versatile multimodal imaging and therapy of cancer.•LNPs empower image-guided drug …
versatile multimodal imaging and therapy of cancer.•LNPs empower image-guided drug …
Rebamipide liposome as an effective ocular delivery system for the management of dry eye disease
H Qiao, Z Xu, M Sun, S Fu, F Zhao, D Wang… - Journal of Drug Delivery …, 2022 - Elsevier
Dry eye disease (DED) is a public health concern that cause ocular discomfort and visual
disturbance, which seriously affect quality of life. Rebamipide (RBM) is one of the drugs …
disturbance, which seriously affect quality of life. Rebamipide (RBM) is one of the drugs …