Metabolic syndrome is manifested by visceral obesity, hypertension, glucose intolerance,
hyperinsulinism, and dyslipidemia. According to the CDC, metabolic syndrome in the US …

Hypertension affects more than one billion people worldwide. Here we identify 113 novel
loci, reporting a total of 2,103 independent genetic signals (P< 5× 10− 8) from the largest …

Much of nutrition research has been conventionally based on the use of simplistic in vitro
systems or animal models, which have been extensively employed in an effort to better …

Dupuytren's disease (DD) is a highly heritable fibrotic disorder of the hand with incompletely
understood etiology. A number of genetic loci, including Wnt signaling members, have been …

Objectives Genome-wide association studies (GWAS) have successfully revealed numerous
susceptibility loci for obesity. However, identifying the causal genes, pathways, and …

Background Twin studies revealed that genetic effects play a role in hand eczema (HE), but
the responsible genetic factors are unknown. Objectives To identify and characterise genetic …

Genome-wide association studies have identified> 3500 associated single nucleotide
polymorphisms and over 1000 independent loci associated with hypertension. These …

Introduction Blood pressure (BP) is a highly heritable trait with over 2000 underlying
genomic loci identified to date. Although the kidney plays a key role, little is known about …

RNA sequencing (RNAseq) technology has become increasingly important in precision
medicine and clinical diagnostics, and emerged as a powerful tool for identifying protein …

Hypertension, a critical global health concern, is characterized by persistent high blood
pressure and is a major cause of cardiovascular events. This perspective explores the …