2014-04-24 Assigned to ONTORII, INC. reassignment ONTORII, INC. ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ZLATEV, IVAN …

This review covers recent progress in the preparation of H-phosphonate mono-and diesters,
basic studies on mechanistic and stereochemical aspects of this class of phosphorus …

Solution The present invention relates to an adjuvant which com prises oligonucleotides
which comprise two to four sequences each represented by 5'-X, CpG X2-3'and has a length …

2017-06-14 Assigned to ONTORII, INC. reassignment ONTORII, INC. ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ZLATEV, IVAN …

Problem The purpose of the present invention is to provide: a chiral nucleic acid adjuvant
having anti-tumor activity; and an anti-tumor agent. Solution The present invention relates to …

First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
43429503&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

CO7H 1/00(2006. 01) CO7H 23/00(2006. 01) CO7B 53/00(2006. 01) CO7H 19/11(2006. 01)
C07H 19/213(2006. 01) CO7H 21/04(2006. 01) CO7D 405/04(2006. 01) C07D …

LLP; **aodong Li; Surin K. Mong (51)(57) ABSTRACT The disclosed and claimed
compounds are chiral auxiliaries useful for efficiently producing a phosphorus atom …

H-phosphonate of structure Ic with a silylating reagent to provide a silyloxyphosphonate,
reacting the silyloxyphos phonate with a bis (thiosulfonate) reagent of structure IVc to …

AJRLEDGULIEGDG-UHFFFAOYSA-M C1= CC= C ([Se][Se] C2= CC= CC= C2) C= C1. N# C
[Se][K]. O= C1 [Se] SC2= CC= CC= C12.[C-]#[N+] CC [Se][Se] CCC# N.[SeH2].[Se]= P (C1 …