[HTML][HTML] Stem cell-based therapy for human diseases

DM Hoang, PT Pham, TQ Bach, ATL Ngo… - Signal transduction and …, 2022 - nature.com
Recent advancements in stem cell technology open a new door for patients suffering from
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …

The immunology of COVID-19: is immune modulation an option for treatment?

J Zhong, J Tang, C Ye, L Dong - The Lancet Rheumatology, 2020 - thelancet.com
In December, 2019, an outbreak of COVID-19 emerged in Wuhan, China and quickly spread
globally. As of May 7, 2020, there were 3 672 238 confirmed infections and 254 045 deaths …

Effect of human umbilical cord-derived mesenchymal stem cells on lung damage in severe COVID-19 patients: a randomized, double-blind, placebo-controlled phase …

L Shi, H Huang, X Lu, X Yan, X Jiang, R Xu… - Signal transduction and …, 2021 - nature.com
Abstract Treatment of severe Coronavirus Disease 2019 (COVID-19) is challenging. We
performed a phase 2 trial to assess the efficacy and safety of human umbilical cord …

Mitochondrial transfer via tunneling nanotubes is an important mechanism by which mesenchymal stem cells enhance macrophage phagocytosis in the in vitro and in …

MV Jackson, TJ Morrison, DF Doherty, DF McAuley… - Stem …, 2016 - academic.oup.com
Mesenchymal stromal cells (MSC) have been reported to improve bacterial clearance in
preclinical models of Acute Respiratory Distress Syndrome (ARDS) and sepsis. The …

MSC therapies for COVID-19: importance of patient coagulopathy, thromboprophylaxis, cell product quality and mode of delivery for treatment safety and efficacy

G Moll, N Drzeniek, J Kamhieh-Milz, S Geissler… - Frontiers in …, 2020 - frontiersin.org
Numerous clinical trials of mesenchymal stromal/stem cells (MSCs) as a new treatment for
coronavirus-induced disease (COVID-19) have been registered recently, most of them …

Differences and similarities between cancer and somatic stem cells: therapeutic implications

F Rossi, H Noren, R Jove, V Beljanski… - Stem cell research & …, 2020 - Springer
Over the last decades, the cancer survival rate has increased due to personalized therapies,
the discovery of targeted therapeutics and novel biological agents, and the application of …

Differential and transferable modulatory effects of mesenchymal stromal cell-derived extracellular vesicles on T, B and NK cell functions

M Di Trapani, G Bassi, M Midolo, A Gatti… - Scientific reports, 2016 - nature.com
Mesenchymal stromal cells (MSCs) are multipotent cells, immunomodulatory stem cells that
are currently used for regenerative medicine and treatment of a number of inflammatory …

Rationale for the clinical use of adipose-derived mesenchymal stem cells for COVID-19 patients

CJ Rogers, RJ Harman, BA Bunnell… - Journal of translational …, 2020 - Springer
In late 2019, a novel coronavirus (SARS-CoV-2) emerged in Wuhan, capital city of Hubei
province in China. Cases of SARS-CoV-2 infection quickly grew by several thousand per …

Mesenchymal stem cells: current clinical progress in ARDS and COVID-19

K **ao, F Hou, X Huang, B Li, ZR Qian, L **e - Stem Cell Research & …, 2020 - Springer
Acute respiratory distress syndrome (ARDS) develops rapidly and has a high mortality rate.
Survivors usually have low quality of life. Current clinical management strategies are …

Mesenchymal stromal cell therapy for liver diseases

M Alfaifi, YW Eom, PN Newsome, SK Baik - Journal of hepatology, 2018 - Elsevier
The therapeutic potential of mesenchymal stromal cells (MSCs) in the treatment of liver
fibrosis is predominantly based on their immunosuppressive properties, and their ability to …