Current research activity in biosensors

H Nakamura, I Karube - Analytical and bioanalytical chemistry, 2003 - Springer
Biosensors consist of a molecular recognition element and a transducer. Since the first
biosensor was developed by Updike and Hicks [1] many biosensors and their associated …

New trends in affinity sensing: aptamers for ligand binding

E Luzi, M Minunni, S Tombelli, M Mascini - TrAC Trends in Analytical …, 2003 - Elsevier
Aptamers are artificial nucleic acid ligands that can be generated against amino acids,
drugs, proteins and other molecules. They are isolated from complex libraries of synthetic …

Aptamer-based biosensors for the detection of HIV-1 Tat protein

S Tombelli, M Minunni, E Luzi, M Mascini - Bioelectrochemistry, 2005 - Elsevier
Two biosensors have been constructed using an RNA aptamer as biorecognition element.
The aptamer, specific for HIV-1 Tat protein, has been immobilised on the gold surface of …

Development of biosensors with aptamers as bio-recognition element: the case of HIV-1 Tat protein

M Minunni, S Tombelli, A Gullotto, E Luzi… - Biosensors and …, 2004 - Elsevier
The in vitro selection of combinatorial libraries of RNA/DNA, has allowed the identification of
specific nucleic acids (aptamers) which bind to a wide range of target molecules with high …

Survey of the year 2001 commercial optical biosensor literature

RL Rich, DG Myszka - Journal of Molecular Recognition, 2002 - Wiley Online Library
We have assembled references of 700 articles published in 2001 that describe work
performed using commercially available optical biosensors. To illustrate the technology's …

Properties of an 'LNA'-modified ricin RNA aptamer

C Förster, M Zydek, M Rothkegel, Z Wu, C Gallin… - Biochemical and …, 2012 - Elsevier
'Locked nucleic acids'(LNAs) are sugar modified nucleic acids containing the 2′-O-4′ C-
methylene-β-d-ribofuranoses. The substitution of RNAs with LNAs leads to an enhanced …

Direct Detection of DNA and DNA‐ligand interaction by impedance spectroscopy

C Witte, F Lisdat - Electroanalysis, 2011 - Wiley Online Library
In this work we present an impedimetric detection system for DNA‐ligand interactions. The
sensor system consists of thiol‐modified single‐stranded DNA chemisorbed to gold …

An improved non-enzymatic hydrogen peroxide sensor based on europium functionalized inorganic hybrid material—Evaluation of optical and electrochemical …

D **, K Sakthivel, S Gandhi, BT Huy, YI Lee - Sensors and Actuators B …, 2016 - Elsevier
We have studied the electrochemical and optical properties of europium; a rare-earth ion
functionalized ordered hybrid mesoporous silica material and evaluated its potential …

Study of cytochrome c-dna interaction–evaluation of binding sites on the redox protein

C Wettstein, C Kyne, AM Doolan, H Möhwald… - Nanoscale, 2014 - pubs.rsc.org
Artificial assemblies consisting of the cationic cytochrome c (cyt c) and double-stranded DNA
are interesting for the field of biohybrid systems because of the high electro-activity of the …

Pushing the detection limits: The evanescent field in surface plasmon resonance and analyte-induced folding observation of long human telomeric repeats

C Schlachter, F Lisdat, M Frohme, VA Erdmann… - Biosensors and …, 2012 - Elsevier
Conventional analysis of molecular interactions by surface plasmon resonance is achieved
by the observation of optical density changes due to analyte binding to the ligand on the …