Scorpion envenomation in Brazil: Current scenario and perspectives for containing an increasing health problem

C Guerra-Duarte, R Saavedra-Langer… - PLoS neglected …, 2023 - journals.plos.org
Opportunistic scorpion species can colonize urban environments, establishing high-density
communities that enhance the chances of human accidents. This scenario has been taking …

Scorpion species of medical importance in the Brazilian Amazon: a review to identify knowledge gaps

JG Martins, GC Santos, REL Procópio… - Journal of Venomous …, 2021 - SciELO Brasil
Scorpionism is a relevant medical condition in Brazil. It is responsible for most accidents
involving venomous animals in the country, which leads to severe symptoms that can evolve …

Acetylcholine, fatty acids, and lipid mediators are linked to COVID-19 severity

MM Pérez, VE Pimentel, CA Fuzo… - The Journal of …, 2022 - journals.aai.org
Lipid and cholinergic mediators are inflammatory regulators, but their role in the
immunopathology of COVID-19 is still unclear. Here, we used human blood and tracheal …

Baccharin and p-coumaric acid from green propolis mitigate inflammation by modulating the production of cytokines and eicosanoids

JC Ferreira, MB Reis, GDP Coelho… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Green propolis is produced by Apis mellifera honeybees
using Baccharis dracunculifolia DC (Asteraceae) as substrate. This Southern Brazilian …

Immunological responses to envenomation

RYM Ryan, J Seymour, A Loukas, JA Lopez… - Frontiers in …, 2021 - frontiersin.org
Venoms are complex mixtures of toxic compounds delivered by bite or sting. In humans, the
consequences of envenomation range from self-limiting to lethal. Critical host defence …

Hyaluronan breakdown by snake venom hyaluronidases: From toxins delivery to immunopathology

F Silva de França, DV Tambourgi - Frontiers in Immunology, 2023 - frontiersin.org
Snake venom enzymes have a broad range of molecular targets in plasma, tissues, and
cells, among which hyaluronan (HA) is outstanding. HA is encountered in the extracellular …

Polymeric Microspheres with High Mass Fraction of Therapeutics Enabled by the Manipulation of Kinetics Factor During Emulsion Droplet Solidification

Z Wei, M Zhu, N Morin, D Wollsten… - Advanced Functional …, 2024 - Wiley Online Library
High drug‐loaded polymeric microspheres hold promise in biomedical fields due to reduced
excipient administration, minimized side effects, and enhanced therapeutical efficacy …

Immunosuppressive therapies in scorpion envenomation: new perspectives for treatment

MB Reis, EC Arantes - Frontiers in Toxicology, 2024 - frontiersin.org
Scorpion envenoming is a relevant and neglected public health problem in some countries.
The use of antivenom is widespread in many regions, targeting specific species of …

EP4 receptor conformation sensor suited for ligand screening and imaging of extracellular prostaglandins

M Kurz, M Ulrich, A Bittner, MM Scharf, J Shao… - Molecular …, 2023 - Elsevier
Prostaglandins are important lipid mediators with a wide range of functions in the human
body. They act mainly via plasma membrane localized prostaglandin receptors, which …