Technological innovations in photochemistry for organic synthesis: flow chemistry, high-throughput experimentation, scale-up, and photoelectrochemistry

L Buglioni, F Raymenants, A Slattery… - Chemical …, 2021 - ACS Publications
Photoinduced chemical transformations have received in recent years a tremendous amount
of attention, providing a plethora of opportunities to synthetic organic chemists. However …

[HTML][HTML] Scale-up of micro-and milli-reactors: An overview of strategies, design principles and applications

Z Dong, Z Wen, F Zhao, S Kuhn, T Noël - Chemical Engineering Science: X, 2021 - Elsevier
Continuous-flow microreactor technology has been embraced by researchers in academia
and industry due to its excellent transport properties and the increased safety and control …

The hitchhiker's guide to flow chemistry∥

MB Plutschack, B Pieber, K Gilmore… - Chemical …, 2017 - ACS Publications
Flow chemistry involves the use of channels or tubing to conduct a reaction in a continuous
stream rather than in a flask. Flow equipment provides chemists with unique control over …

Continuous manufacturing–the Green Chemistry promise?

L Rogers, KF Jensen - Green chemistry, 2019 - pubs.rsc.org
Continuous manufacturing and Green Chemistry, are two promising approaches to
synthesis with underutilized potential that are gaining traction by the wider pharmaceutical …

Toward autonomous laboratories: Convergence of artificial intelligence and experimental automation

Y **e, K Sattari, C Zhang, J Lin - Progress in Materials Science, 2023 - Elsevier
The ever-increasing demand for novel materials with superior properties inspires retrofitting
traditional research paradigms in the era of artificial intelligence and automation. An …

On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system

A Adamo, RL Beingessner, M Behnam, J Chen… - Science, 2016 - science.org
Pharmaceutical manufacturing typically uses batch processing at multiple locations.
Disadvantages of this approach include long production times and the potential for supply …

Flow chemistry—microreaction technology comes of age

KF Jensen - AIChE Journal, 2017 - Wiley Online Library
Over the past two decades, microreaction technology has matured from early devices and
concepts to encompass a wide range of commercial equipment and applications. This …

Continuous flow chemistry: where are we now? Recent applications, challenges and limitations

FM Akwi, P Watts - Chemical Communications, 2018 - pubs.rsc.org
A general outlook of the changing face of chemical synthesis is provided in this article
through recent applications of continuous flow processing in both industry and academia …

Deciding whether to go with the flow: evaluating the merits of flow reactors for synthesis

RL Hartman, JP McMullen… - Angewandte Chemie …, 2011 - Wiley Online Library
The fine chemicals and pharmaceutical industries are transforming how their products are
manufactured, where economically favorable, from traditional batchwise processes to …

Novel process windows for enabling, accelerating, and uplifting flow chemistry

V Hessel, D Kralisch, N Kockmann, T Noël… - …, 2013 - Wiley Online Library
Abstract Novel Process Windows make use of process conditions that are far from
conventional practices. This involves the use of high temperatures, high pressures, high …