Digital twins for health: a sco** review

E Katsoulakis, Q Wang, H Wu, L Shahriyari… - NPJ digital …, 2024 - nature.com
The use of digital twins (DTs) has proliferated across various fields and industries, with a
recent surge in the healthcare sector. The concept of digital twin for health (DT4H) holds …

Digital twins in medicine

R Laubenbacher, B Mehrad, I Shmulevich… - Nature Computational …, 2024 - nature.com
Medical digital twins, which are potentially vital for personalized medicine, have become a
recent focus in medical research. Here we present an overview of the state of the art in …

Exploring approaches for predictive cancer patient digital twins: Opportunities for collaboration and innovation

EA Stahlberg, M Abdel-Rahman, B Aguilar… - Frontiers in Digital …, 2022 - frontiersin.org
We are rapidly approaching a future in which cancer patient digital twins will reach their
potential to predict cancer prevention, diagnosis, and treatment in individual patients. This …

Patient-specific, mechanistic models of tumor growth incorporating artificial intelligence and big data

G Lorenzo, SR Ahmed, DA Hormuth II… - Annual Review of …, 2024 - annualreviews.org
Despite the remarkable advances in cancer diagnosis, treatment, and management over the
past decade, malignant tumors remain a major public health problem. Further progress in …

Harnessing progress in radiotherapy for global cancer control

DA Jaffray, F Knaul, M Baumann, M Gospodarowicz - Nature Cancer, 2023 - nature.com
The pace of technological innovation over the past three decades has transformed the field
of radiotherapy into one of the most technologically intense disciplines in medicine …

MRI-based digital models forecast patient-specific treatment responses to neoadjuvant chemotherapy in triple-negative breast cancer

C Wu, AM Jarrett, Z Zhou, N Elshafeey… - Cancer …, 2022 - aacrjournals.org
Triple-negative breast cancer (TNBC) is persistently refractory to therapy, and methods to
improve targeting and evaluation of responses to therapy in this disease are needed. Here …

A review of mechanistic learning in mathematical oncology

J Metzcar, CR Jutzeler, P Macklin… - Frontiers in …, 2024 - frontiersin.org
Mechanistic learning refers to the synergistic combination of mechanistic mathematical
modeling and data-driven machine or deep learning. This emerging field finds increasing …

Predictive digital twin for optimizing patient-specific radiotherapy regimens under uncertainty in high-grade gliomas

A Chaudhuri, G Pash, DA Hormuth… - Frontiers in Artificial …, 2023 - frontiersin.org
We develop a methodology to create data-driven predictive digital twins for optimal risk-
aware clinical decision-making. We illustrate the methodology as an enabler for an …

Theranostic digital twins: Concept, framework and roadmap towards personalized radiopharmaceutical therapies

H Abdollahi, F Yousefirizi, I Shiri, J Brosch-Lenz… - …, 2024 - pmc.ncbi.nlm.nih.gov
Radiopharmaceutical therapy (RPT) is a rapidly develo** field of nuclear medicine, with
several RPTs already well established in the treatment of several different types of cancers …

[PDF][PDF] Artificial intelligence and healthcare simulation: the shifting landscape of medical education

A Hamilton - Cureus, 2024 - cureus.com
The impact of artificial intelligence (AI) will be felt not only in the arena of patient care and
deliverable therapies but will also be uniquely disruptive in medical education and …