Early neurodevelopment of HIV-exposed uninfected children in the era of antiretroviral therapy: a systematic review and meta-analysis

CJ Wedderburn, E Weldon, C Bertran-Cobo… - The Lancet Child & …, 2022 - thelancet.com
Background There are 15· 4 million children who are HIV-exposed and uninfected
worldwide. Early child development crucially influences later academic and socioeconomic …

Growth and neurodevelopment of HIV-exposed uninfected children: a conceptual framework

CJ Wedderburn, C Evans, S Yeung, DM Gibb… - Current HIV/AIDS …, 2019 - Springer
Abstract Purpose of Review The population of HIV-exposed uninfected (HEU) children is
expanding rapidly, and over one million HEU infants are born each year globally. Several …

Association of birth during the COVID-19 pandemic with neurodevelopmental status at 6 months in infants with and without in utero exposure to maternal SARS-CoV-2 …

LC Shuffrey, MR Firestein, MH Kyle, A Fields… - JAMA …, 2022 - jamanetwork.com
Importance Associations between in utero exposure to maternal SARS-CoV-2 infection and
neurodevelopment are speculated, but currently unknown. Objective To examine the …

Estimates of the global population of children who are HIV-exposed and uninfected, 2000–18: a modelling study

AL Slogrove, KM Powis, LF Johnson… - The Lancet Global …, 2020 - thelancet.com
Background Children who are HIV-exposed uninfected (HEU) have higher morbidity and
mortality than children who are HIV-unexposed and uninfected despite safer breastfeeding …

Association of in utero HIV exposure with child brain structure and language development: a South African birth cohort study

CJ Wedderburn, S Yeung, S Subramoney, JP Fouche… - BMC medicine, 2024 - Springer
Background There is a growing population of children with in utero HIV exposure who are at
risk of poor neurodevelopmental outcomes despite avoiding HIV infection. However, the …

Early child development in children who are HIV‐exposed uninfected compared to children who are HIV‐unexposed: observational sub‐study of a cluster‐randomized …

R Ntozini, J Chandna, C Evans… - Journal of the …, 2020 - Wiley Online Library
Introduction Exposure to maternal HIV may affect early child development (ECD), although
previous studies have reported heterogeneous findings. We evaluated ECD among children …

Early structural brain development in infants exposed to HIV and antiretroviral therapy in utero in a South African birth cohort

CJ Wedderburn, NA Groenewold… - Journal of the …, 2022 - Wiley Online Library
Introduction There is a growing population of children who are HIV‐exposed and uninfected
(HEU) with the successful expansion of antiretroviral therapy (ART) use in pregnancy …

[HTML][HTML] In-utero exposure to indoor air pollution or tobacco smoke and cognitive development in a South African birth cohort study

GM Christensen, C Rowcliffe, J Chen, A Vanker… - Science of the total …, 2022 - Elsevier
Abstract Background and Aims There is increasing evidence indicating that air pollution
exposure is associated with neuronal damage. Since pregnancy is a critical window of …

[HTML][HTML] Association of maternal and infant inflammation with neurodevelopment in HIV-exposed uninfected children in a South African birth cohort

T Sevenoaks, CJ Wedderburn, KA Donald… - Brain, Behavior, and …, 2021 - Elsevier
HIV-exposed uninfected (HEU) children may have altered immune regulation and poorer
neurodevelopment outcomes compared to their HIV-unexposed (HU) counterparts …

Leveraging HIV care Infrastructures for integrated chronic disease and pandemic management in sub-Saharan Africa

MA Brault, SH Vermund, MH Aliyu, SB Omer… - International journal of …, 2021 - mdpi.com
In Sub-Saharan Africa, communicable and other tropical infectious diseases remain major
challenges apart from the continuing HIV/AIDS epidemic. Recognition and prevalence of …