Adaptive response of T and B cells in atherosclerosis

DFJ Ketelhuth, GK Hansson - Circulation research, 2016 - Am Heart Assoc
Atherosclerosis is a chronic inflammatory disease that is initiated by the retention and
accumulation of cholesterol-containing lipoproteins, particularly low-density lipoprotein, in …

Immune and inflammatory mechanisms of atherosclerosis

E Galkina, K Ley - Annual review of immunology, 2009 - annualreviews.org
Atherosclerosis is an inflammatory disease of the wall of large-and medium-sized arteries
that is precipitated by elevated levels of low-density lipoprotein (LDL) cholesterol in the …

PECAM-1 stabilizes blood-brain barrier integrity and favors paracellular T-cell diapedesis across the blood-brain barrier during neuroinflammation

I Wimmer, S Tietz, H Nishihara, U Deutsch… - Frontiers in …, 2019 - frontiersin.org
Breakdown of the blood-brain barrier (BBB) and increased immune cell trafficking into the
central nervous system (CNS) are hallmarks of the pathogenesis of multiple sclerosis (MS) …

Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis

R Klingenberg, N Gerdes, RM Badeau… - The Journal of …, 2013 - Am Soc Clin Investig
Atherosclerosis is a chronic inflammatory disease promoted by hyperlipidemia. Several
studies support FOXP3-positive regulatory T cells (Tregs) as inhibitors of atherosclerosis; …

Targeting the Immune System in Atherosclerosis: JACC State-of-the-Art Review

TX Zhao, Z Mallat - Journal of the American College of Cardiology, 2019 - jacc.org
Atherosclerosis has long been known as an inflammatory disease. However, whether
targeting inflammation improves outcomes was unproven until the recent results of CANTOS …

Endothelial barrier function and leukocyte transmigration in atherosclerosis

TJ Sluiter, JD van Buul, S Huveneers, PHA Quax… - Biomedicines, 2021 - mdpi.com
The vascular endothelium is a highly specialized barrier that controls passage of fluids and
migration of cells from the lumen into the vessel wall. Endothelial cells assist leukocytes to …

Allicin-loaded intelligent hydrogel coating improving vascular implant performance

X Han, B Lu, D Zou, X Luo, L Liu, MF Maitz… - … Applied Materials & …, 2023 - ACS Publications
Coronary atherosclerosis is closely related to inflammation and oxidative stress. Owing to
poor biocompatibility, lack of personalized treatment, and late toxic side effects, traditional …

Neutrophil–lymphocyte ratio as a predictor of major adverse cardiac events among diabetic population: a 4-year follow-up study

B Azab, V Chainani, N Shah, JT McGinn - Angiology, 2013 - journals.sagepub.com
The neutrophil–lymphocyte ratio (NLR) is an inflammatory marker of major adverse cardiac
events (MACEs) in both acute coronary syndromes and stable coronary artery disease. The …

[PDF][PDF] CD31: beyond a marker for endothelial cells

L Liu, GP Shi - Cardiovasc Res, 2012 - scholar.archive.org
CD31 is a 130 kDa platelet–endothelial cell (EC) adhesion molecule that was initially
identified from ECs and platelets 1 and later from blood leucocytes. 2 Mature CD31 contains …

An immunologist's guide to CD31 function in T-cells

FM Marelli-Berg, M Clement, C Mauro… - Journal of cell …, 2013 - journals.biologists.com
Although it is expressed by all leukocytes, including T-, B-lymphocytes and dendritic cells,
the immunoglobulin-like receptor CD31 is generally regarded by immunologists as a marker …