[HTML][HTML] Antimicrobial peptides for combating drug-resistant bacterial infections

J Xuan, W Feng, J Wang, R Wang, B Zhang, L Bo… - Drug Resistance …, 2023 - Elsevier
The problem of drug resistance due to long-term use of antibiotics has been a concern for
years. As this problem grows worse, infections caused by multiple bacteria are expanding …

[HTML][HTML] Antimicrobial peptides—mechanisms of action, antimicrobial effects and clinical applications

J Talapko, T Meštrović, M Juzbašić, M Tomas, S Erić… - Antibiotics, 2022 - mdpi.com
The growing emergence of antimicrobial resistance represents a global problem that not
only influences healthcare systems but also has grave implications for political and …

Insect-pathogen crosstalk and the cellular-molecular mechanisms of insect immunity: uncovering the underlying signaling pathways and immune regulatory function of …

DK Mahanta, TK Bhoi, J Komal, I Samal… - Frontiers in …, 2023 - frontiersin.org
Multicellular organisms are constantly subjected to pathogens that might be harmful.
Although insects lack an adaptive immune system, they possess highly effective anti …

SiameseCPP: a sequence-based Siamese network to predict cell-penetrating peptides by contrastive learning

X Zhang, L Wei, X Ye, K Zhang, S Teng… - Briefings in …, 2023 - academic.oup.com
Abstract Background Cell-penetrating peptides (CPPs) have received considerable attention
as a means of transporting pharmacologically active molecules into living cells without …

Medium-sized peptides from microbial sources with potential for antibacterial drug development

J Chen, W Wang, X Hu, Y Yue, X Lu, C Wang… - Natural Product …, 2024 - pubs.rsc.org
Covering: 1993 to the end of 2022 As the rapid development of antibiotic resistance shrinks
the number of clinically available antibiotics, there is an urgent need for novel options to fill …

Heterologous expression of the novel dimeric antimicrobial peptide LIG in Pichia pastoris

L Zhao, L Li, M Hu, Y Fang, N Dong, A Shan - Journal of Biotechnology, 2024 - Elsevier
The antimicrobial peptide (AMP) LI is a fusion product of antimicrobial peptide LL37
produced by human neutrophils and Indolicidin secreted by bovine neutrophils. LI retained …