Rheumatoid arthritis is a heterogeneous disease, which can be, based on data combining
genetic risk factors and autoantibodies, sub-classified into ACPA-positive and-negative RA …

Despite nearly three decades of advances in the management of rheumatoid arthritis (RA), a
substantial minority of patients are exposed to multiple DMARDs without necessarily …

Rheumatoid arthritis (RA) is considered a chronic systemic, multi-factorial, inflammatory, and
progressive autoimmune disease affecting many people worldwide. While patients show …

Osteoarthritis (OA) is one of the most common causes of disability around the globe,
especially in aging populations. The main symptoms of OA are pain and loss of motion and …

Although elevated levels of anti-citrullinated protein antibodies (ACPAs) are a hallmark of
rheumatoid arthritis (RA), the in vivo functions of these antibodies remain unclear. Here, we …

Rheumatoid arthritis is a chronic autoimmune syndrome associated with several genetic,
epigenetic, and environmental factors affecting the articular joints contributing to cartilage …

Chronic pain, encompassing conditions, such as low back pain, arthritis, persistent post-
surgical pain, fibromyalgia, and neuropathic pain disorders, is highly prevalent but remains …

The leukocyte Fcγ receptor (FcγR)-mediated response is important for the efficacy of
therapeutic antibodies; however, little is known about the role of FcγRs in other cell types …

Inflammation, the body's primary defensive response system to injury and infection, is
triggered by molecular signatures of microbes and tissue injury. These molecules also …

Inflammatory arthritis is a growing worldwide concern, afflicting millions of individuals and
leading to a depreciating quality of life, significant morbidity, and subsequent healthcare …