NR5A2 connects zygotic genome activation to the first lineage segregation in totipotent embryos
Zygotic genome activation (ZGA) marks the beginning of the embryonic program for a
totipotent embryo, which gives rise to the inner cell mass (ICM) where pluripotent epiblast …
totipotent embryo, which gives rise to the inner cell mass (ICM) where pluripotent epiblast …
Advances in understanding the regulation of pluripotency fate transition in embryonic stem cells
Y Jia, Y Yu, L Guan - Frontiers in Cell and Developmental Biology, 2024 - frontiersin.org
Embryonic stem cells (ESCs) sourced from the inner cell mass of blastocysts, are akin to this
tissue in function but lack the capacity to form all extraembryonic structures. mESCs are …
tissue in function but lack the capacity to form all extraembryonic structures. mESCs are …
NR5A2 connects genome activation to the first lineage segregation in early mouse development
After fertilization, zygotic genome activation (ZGA) marks the beginning of the embryonic
program for a totipotent embryo, which further gives rise to the pluripotent embryonic …
program for a totipotent embryo, which further gives rise to the pluripotent embryonic …
A single cell transcriptomic fingerprint of stressed premature, imbalanced differentiation of embryonic stem cells
XL Ruden, A Singh, T Marben, W Tang… - Birth Defects …, 2024 - Wiley Online Library
Background Miscarriages cause a greater loss‐of‐life than cardiovascular diseases, but
knowledge about environmentally induced miscarriages is limited. Cultured naïve …
knowledge about environmentally induced miscarriages is limited. Cultured naïve …