Although there has been substantial improvement in atherosclerotic cardiovascular disease
(ASCVD) outcomes in recent decades, ASCVD remains the leading cause of morbidity and …

Cardiovascular disease is the leading contributor to years lost due to disability or premature
death among adults. Current efforts focus on risk prediction and risk factor mitigation ‚which …

Background Five modifiable risk factors are associated with cardiovascular disease and
death from any cause. Studies using individual-level data to evaluate the regional and sex …

Background The use of aspirin in the primary prevention of cardiovascular events remains
controversial. We aimed to assess the efficacy and safety of aspirin versus placebo in …

Polygenic risk scores (PRSs), which often aggregate results from genome-wide association
studies, can bridge the gap between initial discovery efforts and clinical applications for the …

Importance The incremental value of polygenic risk scores in addition to well-established
risk prediction models for coronary artery disease (CAD) is uncertain. Objective To examine …

Artificial intelligence (AI) has the potential to transform every facet of cardiovascular practice
and research. The exponential rise in technology powered by AI is defining new frontiers in …

Risk assessment is a critical step in the current approach to primary prevention of
atherosclerotic cardiovascular disease. Knowledge of the 10-year risk for atherosclerotic …

Cardiovascular-kidney-metabolic (CKM) syndrome is a novel construct recently defined by
the American Heart Association in response to the high prevalence of metabolic and kidney …

Race-based medicine has been pervasively interwoven into the fabric of health care
delivery in the United States for more than 400 years. Race is a historically derived social …