Palytoxin-group toxins (PlTX) exert their potent biological activity by altering mechanisms of
ion homeostasis in excitable and non-excitable tissues. This review will describe major …

Palytoxin is a marine toxin originally isolated from the zoantharians of the genus Palythoa,
but now is found in marine organisms ranging from dinoflagellates to fishes. With a MW of …

Na, K‐ATPase is an ubiquitous enzyme actively transporting Na‐ions out of the cell in
exchange for K‐ions, thereby maintaining their concentration gradients across the cell …

Cytoskeleton is a dynamic structure essential for a wide variety of normal cellular processes,
including the maintenance of cell shape and morphology, volume regulation, membrane …

P‐type ATPases constitute a ubiquitous superfamily of cation transport enzymes,
responsible for carrying out actions of paramount importance in biology such as ion …

Cation fluxes appear to play a key role in palytoxin-induced signal. There are other cellular
targets that have not been described as well as the biochemical signaling cascades that …

Palytoxin is one of the largest non-proteinaceous natural products and one of the most
potent toxins that have ever been found. It was first discovered in zoantharians of the genus …

Whereas cation transport by the electrogenic membrane transporter Na+, K+-ATPase can be
measured by electrophysiology, the electroneutrally operating gastric H+, K+-ATPase is …

A severe harmful algal bloom (HAB) devastated marine life in the Wellington Harbour in the
late summer 1998. A novel species of Karenia dinoflagellates was isolated from this HAB …

AVIS et RAPPORT de l'Anses relatif à l’élaboration de VTR pour la palytoxine (CAS n 77734-91-9)
Page 1 Connaître, évaluer, protéger Valeurs toxicologiques de référence Avis de l’Anses …