Review of adaptive optics OCT (AO-OCT): principles and applications for retinal imaging

M Pircher, RJ Zawadzki - Biomedical optics express, 2017 - opg.optica.org
In vivo imaging of the human retina with a resolution that allows visualization of cellular
structures has proven to be essential to broaden our knowledge about the physiology of this …

Random-access wide-field mesoscopy for centimetre-scale imaging of biodynamics with subcellular resolution

R Shi, X Chen, J Deng, J Liang, K Fan, F Zhou… - Nature …, 2024 - nature.com
Benefitting from the advantages of high imaging throughput and low cost, wide-field
microscopy has become indispensable in biomedical studies. However, it remains …

Fluorescent wavefront sha** using incoherent iterative phase conjugation

D Aizik, I Gkioulekas, A Levin - Optica, 2022 - opg.optica.org
Wavefront sha** correction makes it possible to image fluorescent particles deep inside
scattering tissue. This requires determining a correction mask to be placed in both the …

Wavefront sensor-less adaptive optics using deep reinforcement learning

E Durech, W Newberry, J Franke… - Biomedical optics …, 2021 - opg.optica.org
Image degradation due to wavefront aberrations can be corrected with adaptive optics (AO).
In a typical AO configuration, the aberrations are measured directly using a Shack-Hartmann …

Depth-resolved optimization of a real-time sensorless adaptive optics optical coherence tomography

A Camino, R Ng, J Huang, Y Guo, S Ni, Y Jia… - Optics letters, 2020 - opg.optica.org
Sensorless adaptive optics optical coherence tomography (AO-OCT) is a technology to
image retinal tissue with high resolution by compensating ocular aberrations without …

Lens-based wavefront sensorless adaptive optics swept source OCT

Y Jian, S Lee, MJ Ju, M Heisler, W Ding, RJ Zawadzki… - Scientific reports, 2016 - nature.com
Optical coherence tomography (OCT) has revolutionized modern ophthalmology, providing
depth resolved images of the retinal layers in a system that is suited to a clinical …

Sensorless adaptive optics multimodal en-face small animal retinal imaging

DJ Wahl, R Ng, MJ Ju, Y Jian… - Biomedical Optics Express, 2018 - opg.optica.org
Vision researchers often use small animals due to the availability of many transgenic strains
that model human diseases or express biomarkers. Adaptive optics (AO) enables non …

Wide-field retinal optical coherence tomography with wavefront sensorless adaptive optics for enhanced imaging of targeted regions

J Polans, B Keller, OM Carrasco-Zevallos… - Biomedical optics …, 2016 - opg.optica.org
The peripheral retina of the human eye offers a unique opportunity for assessment and
monitoring of ocular diseases. We have developed a novel wide-field (> 70°) optical …

Online optimization with costly and noisy measurements using random Fourier expansions

L Bliek, HRGW Verstraete… - IEEE transactions on …, 2016 - ieeexplore.ieee.org
This paper analyzes data-based online nonlinear extremum-seeker (DONE), an online
optimization algorithm that iteratively minimizes an unknown function based on costly and …

Wavefront sensorless adaptive optics OCT with the DONE algorithm for in vivo human retinal imaging

HRGW Verstraete, M Heisler, MJ Ju, D Wahl… - Biomedical optics …, 2017 - opg.optica.org
In this report, which is an international collaboration of OCT, adaptive optics, and control
research, we demonstrate the Data-based Online Nonlinear Extremum-seeker (DONE) …