[HTML][HTML] Toward individualized connectomes of brain morphology

J Wang, Y He - Trends in Neurosciences, 2024 - cell.com
The morphological brain connectome (MBC) delineates the coordinated patterns of local
morphological features (such as cortical thickness) across brain regions. While classically …

Individual‐level brain morphological similarity networks: current methodologies and applications

M Cai, J Ma, Z Wang, Y Zhao, Y Zhang… - CNS Neuroscience …, 2023 - Wiley Online Library
Aims The human brain is an extremely complex system in which neurons, clusters of
neurons, or regions are connected to form a complex network. With the development of …

Neuroimaging biomarkers define neurophysiological subtypes with distinct trajectories in schizophrenia

Y Jiang, J Wang, E Zhou, L Palaniyappan, C Luo… - Nature Mental …, 2023 - nature.com
Technical developments and improved access to neuroimaging techniques have brought us
closer to understanding the neuropathological origins of schizophrenia. Using data-driven …

Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium

D Schijven, MC Postema, M Fukunaga… - Proceedings of the …, 2023 - pnas.org
Left–right asymmetry is an important organizing feature of the healthy brain that may be
altered in schizophrenia, but most studies have used relatively small samples and …

Environmental neuroscience linking exposome to brain structure and function underlying cognition and behavior

F Liu, J Xu, L Guo, W Qin, M Liang, G Schumann… - Molecular …, 2023 - nature.com
Individual differences in human brain structure, function, and behavior can be attributed to
genetic variations, environmental exposures, and their interactions. Although genome-wide …

Cell type-specific manifestations of cortical thickness heterogeneity in schizophrenia

MA Di Biase, MP Geaghan, WR Reay, J Seidlitz… - Molecular …, 2022 - nature.com
Brain morphology differs markedly between individuals with schizophrenia, but the cellular
and genetic basis of this heterogeneity is poorly understood. Here, we sought to determine …

Biological subty** of psychiatric syndromes as a pathway for advances in drug discovery and personalized medicine

W Zhang, JA Sweeney, JR Bishop, Q Gong… - Nature Mental …, 2023 - nature.com
Every common psychiatric syndrome is genetically, neurobiologically and clinically
heterogeneous. This heterogeneity may reflect the dimensional variability of a single illness …

Neuroimaging epicenters as potential sites of onset of the neuroanatomical pathology in schizophrenia

Y Jiang, L Palaniyappan, C Luo, X Chang, J Zhang… - Science …, 2024 - science.org
Schizophrenia lacks a clear definition at the neuroanatomical level, capturing the sites of
origin and progress of this disorder. Using a network-theory approach called epicenter …

Leveraging machine learning for gaining neurobiological and nosological insights in psychiatric research

J Chen, KR Patil, BTT Yeo, SB Eickhoff - Biological psychiatry, 2023 - Elsevier
Much attention is currently devoted to develo** diagnostic classifiers for mental disorders.
Complementing these efforts, we highlight the potential of machine learning to gain …

Identifying the individual metabolic abnormities from a systemic perspective using whole-body PET imaging

T Sun, Z Wang, Y Wu, F Gu, X Li, Y Bai, C Shen… - European Journal of …, 2022 - Springer
Introduction Distinct physiological states arise from complex interactions among the various
organs present in the human body. PET is a non-invasive modality with numerous …