[HTML][HTML] HRP2: transforming malaria diagnosis, but with caveats
The major growth in point-of-care malaria diagnosis over the past decade has been based
on immunochromatographic malaria rapid diagnostic tests (mRDTs), which generally detect …
on immunochromatographic malaria rapid diagnostic tests (mRDTs), which generally detect …
The MEME suite
The MEME Suite is a powerful, integrated set of web-based tools for studying sequence
motifs in proteins, DNA and RNA. Such motifs encode many biological functions, and their …
motifs in proteins, DNA and RNA. Such motifs encode many biological functions, and their …
Dense granules: are they key organelles to help understand the parasitophorous vacuole of all apicomplexa parasites?
C Mercier, KDZ Adjogble, W Däubener - International journal for …, 2005 - Elsevier
Together with micronemes and rhoptries, dense granules are specialised secretory
organelles of Apicomplexa parasites. Among Apicomplexa, Plasmodium represents a model …
organelles of Apicomplexa parasites. Among Apicomplexa, Plasmodium represents a model …
Targeting malaria virulence and remodeling proteins to the host erythrocyte
To establish infection in the host, malaria parasites export remodeling and virulence proteins
into the erythrocyte. These proteins can traverse a series of membranes, including the …
into the erythrocyte. These proteins can traverse a series of membranes, including the …
A host-targeting signal in virulence proteins reveals a secretome in malarial infection
Malaria parasites secrete proteins across the vacuolar membrane into the erythrocyte,
inducing modifications linked to disease and parasite survival. We identified an 11–amino …
inducing modifications linked to disease and parasite survival. We identified an 11–amino …
Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of the Mutualistic Root Symbiont Piriformospora indica
Recent sequencing projects have provided deep insight into fungal lifestyle-associated
genomic adaptations. Here we report on the 25 Mb genome of the mutualistic root symbiont …
genomic adaptations. Here we report on the 25 Mb genome of the mutualistic root symbiont …
A newly discovered protein export machine in malaria parasites
Several hundred malaria parasite proteins are exported beyond an encasing vacuole and
into the cytosol of the host erythrocyte, a process that is central to the virulence and viability …
into the cytosol of the host erythrocyte, a process that is central to the virulence and viability …
Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2′-O-methylation by nsp16/nsp10 protein complex
Y Chen, C Su, M Ke, X **, L Xu, Z Zhang, A Wu… - PLoS …, 2011 - journals.plos.org
The 5′-cap structure is a distinct feature of eukaryotic mRNAs, and eukaryotic viruses
generally modify the 5′-end of viral RNAs to mimic cellular mRNA structure, which is …
generally modify the 5′-end of viral RNAs to mimic cellular mRNA structure, which is …
Localization of organellar proteins in Plasmodium falciparum using a novel set of transfection vectors and a new immunofluorescence fixation method
The apicoplast and mitochondrion of the malaria parasite Plasmodium falciparum are
important intracellular organelles and targets of several anti-malarial drugs. In recent years …
important intracellular organelles and targets of several anti-malarial drugs. In recent years …
N-terminal processing of proteins exported by malaria parasites
HH Chang, AM Falick, PM Carlton, JW Sedat… - Molecular and …, 2008 - Elsevier
Malaria parasites utilize a short N-terminal amino acid motif termed the Plasmodium export
element (PEXEL) to export an array of proteins to the host erythrocyte during blood stage …
element (PEXEL) to export an array of proteins to the host erythrocyte during blood stage …