Brownian dynamics simulations of biological molecules
GA Huber, JA McCammon - Trends in chemistry, 2019 - cell.com
Brownian dynamics (BD) is a technique for carrying out computer simulations of physical
systems that are driven by thermal fluctuations. Biological systems at the macromolecular …
systems that are driven by thermal fluctuations. Biological systems at the macromolecular …
Protein interactions with negatively charged inorganic surfaces
K Kubiak-Ossowska, B Jachimska… - Current opinion in …, 2019 - Elsevier
Protein adsorption on charged inorganic solid materials has recently attracted enormous
interest owing to its various possible applications, including drug delivery and biomaterial …
interest owing to its various possible applications, including drug delivery and biomaterial …
Photonic-plasmonic hybrid single-molecule nanosensor measures the effect of fluorescent labels on DNA-protein dynamics
Current methods to study molecular interactions require labeling the subject molecules with
fluorescent reporters. However, the effect of the fluorescent reporters on molecular dynamics …
fluorescent reporters. However, the effect of the fluorescent reporters on molecular dynamics …
Time Evolution of Ultrasmall Gold Nanoparticle–Protein Interactions
To date, much effort has been devoted toward the study of protein corona formation onto
large gold nanoparticles (GNPs). However, the protein corona concept breaks down for …
large gold nanoparticles (GNPs). However, the protein corona concept breaks down for …
Adsorption-Driven Deformation and Footprints of the RBD Proteins in SARS-CoV-2 Variants on Biological and Inanimate Surfaces
Respiratory viruses, carried through airborne microdroplets, frequently adhere to surfaces,
including plastics and metals. However, our understanding of the interactions between …
including plastics and metals. However, our understanding of the interactions between …
pH-Induced reorientation of cytochrome c on silica nanoparticles
The orientation of cytochrome c molecules at the surface of silica nanoparticles was studied
in a wide pH range by combining small-angle neutron scattering, adsorption measurements …
in a wide pH range by combining small-angle neutron scattering, adsorption measurements …
[HTML][HTML] Small, smaller, smallest: Miniaturization of chromatographic process development
TC Silva, M Eppink, M Ottens - Journal of Chromatography A, 2022 - Elsevier
Biopharmaceuticals are becoming increasingly important in modern healthcare. Monoclonal
antibodies (mAb) are one of the most widely used therapeutic proteins and are important for …
antibodies (mAb) are one of the most widely used therapeutic proteins and are important for …
Controlling experimental parameters to improve characterization of biomaterial fouling
Uncontrolled protein adsorption and cell binding to biomaterial surfaces may lead to
degradation, implant failure, infection, and deleterious inflammatory and immune responses …
degradation, implant failure, infection, and deleterious inflammatory and immune responses …
Protein-Rich Rafts in Hybrid Polymer/Lipid Giant Unilamellar Vesicles
N Otrin, L Otrin, C Bednarz, TK Träger… - …, 2024 - ACS Publications
Considerable attention has been dedicated to lipid rafts due to their importance in numerous
cell functions such as membrane trafficking, polarization, and signaling. Next to studies in …
cell functions such as membrane trafficking, polarization, and signaling. Next to studies in …
Dominant albumin–surface interactions under independent control of surface charge and wettability
Understanding protein adsorption behaviors on solid surfaces constitutes an important step
toward development of efficacious and biocompatible medical devices. Both surface charge …
toward development of efficacious and biocompatible medical devices. Both surface charge …