Synthesis, structure–activity relationships, and in vitro antibacterial and antifungal activity evaluations of novel pyrazole carboxylic and dicarboxylic acid derivatives

S Mert, R Kasımoğulları, T Iça, F Çolak, A Altun… - European journal of …, 2014 - Elsevier
A series of pyrazole-3-carboxylic acid and pyrazole-3, 4-dicarboxylic acid derivatives were
synthesized, the structures were confirmed by their NMR (1 H and 13 C) and FT-IR spectra …

Microwave-assisted synthesis and bioevaluation of new sulfonamides

HI Gul, C Yamali, F Yesilyurt, H Sakagami… - Journal of enzyme …, 2017 - Taylor & Francis
Abstract In this study, 4-[5-(4-hydroxyphenyl)-3-aryl-4, 5-dihydro-1 H-pyrazol-1-yl]
benzenesulfonamide derivatives (8-14) were synthesized for the first time by microwave …

Designing, synthesis and bioactivities of 4-[3-(4-hydroxyphenyl)-5-aryl-4, 5-dihydro-pyrazol-1-yl] benzenesulfonamides

HI Gul, E Mete, SE Eren, H Sakagami… - Journal of enzyme …, 2017 - Taylor & Francis
Abstract In this study, 4-[3-(4-hydroxyphenyl)-5-aryl-4, 5-dihydro-pyrazol-1-yl]
benzenesulfonamide (1–9) types compounds were synthesized and their chemical …

Synthesis, molecular docking and molecular dynamics simulations, drug-likeness studies, ADMET prediction and biological evaluation of novel pyrazole …

İ Yetek, S Mert, E Tunca, A Bayrakdar… - Molecular Diversity, 2024 - Springer
Pyrazoles are unique bioactive molecules with a versatile biological profile and they have
gained an important place on pharmaceutical chemistry. Pyrazole compounds containing …

The synthesis of novel pyrazole-3, 4-dicarboxamides bearing 5-amino-1, 3, 4-thiadiazole-2-sulfonamide moiety with effective inhibitory activity against the isoforms of …

S Mert, Z Alım, MM İşgör, Ş Beydemir… - Bioorganic chemistry, 2016 - Elsevier
Abstract A series of 1-(3-substituted-phenyl)-5-phenyl-N 3, N 4-bis (5-sulfamoyl-1, 3, 4-
thiadiazol-2-yl)-1H-pyrazole-3, 4-dicarboxamides (4–15) were synthesized. The structures of …

Diazenyl derivatives and their complexes as anticancer agents

H Kaur, S Yadav, B Narasimhan - Anti-Cancer Agents in …, 2016 - benthamdirect.com
In the past years, many diazenyl compounds (ie diazenecarboxamides, diazeniumdiolate
prodrugs, diazenyl complexes etc.) have been prepared for the evaluation of their cytotoxic …

Development of new targeted nanotherapy combined with magneto-fluorescent nanoparticles against colorectal cancer

GA Marcelo, D Montpeyó, J Galhano… - International Journal of …, 2023 - mdpi.com
The need for non-invasive therapies capable of conserving drug efficiency and stability
while having specific targetability against colorectal cancer (CRC), has made nanoparticles …

Synthesis and antiproliferative activities of some pyrazole-sulfonamide derivatives

S Mert, AŞ Yağlıoğlu, I Demirtas… - Medicinal Chemistry …, 2014 - Springer
In this study, a series of pyrazole-sulfonamide derivatives were designed and synthesized
from 1-(4-aminophenyl)-4-benzoyl-5-phenyl-N-(5-sulfamoyl-1, 3, 4-thiadiazol-2-yl)-1 H …

Reactions of some pyrazole-3-carboxylic acids with various N,N'-binucleophiles and investigation of their antiproliferative activities

R Kasımoğulları, M Maden, AŞ Yağlıoğlu, S Mert… - 2015 - nopr.niscpr.res.in
Synthesis, characterization, and antiproliferative activity evaluation of a series of novel
pyrazole bis-carboxamide derivatives (8–12) have been described. Synthesized molecules …

Synthesis of 2-(4-Methyl-Phenoxymethyl) Benzoic Acid; Cresol and its Metal Coordinate Complexes

S Waheed, F Nazakat, N Abbas, M Nadeem… - FRONTIERS IN …, 2024 - fcs.wum.edu.pk
A series of phenoxymethylbenzoic acid derivatives were synthesized by reacting p-cresol
with phthalide. The resulting phenoxymethyl benzoic acid was converted into corresponding …