Innate and adaptive immunity represent a harmonic counterbalanced system involved in the
induction, progression, and possibly resolution of the inflammatory reaction that characterize …

Macrophages are dynamic cells that play critical roles in the induction and resolution of
sterile inflammation. In this review, we will compile and interpret recent findings on the …

Synovial tissue macrophages (STMs) were principally recognized as having a pro-
inflammatory role in rheumatoid arthritis (RA), serving as the main producers of pathogenic …

Rheumatoid arthritis (RA) is one of more than 100 types of arthritis. This chronic autoimmune
disorder affects the lining of synovial joints in about 0.5% of people and may induce severe …

Gut microbiota dysbiosis is associated with the development of rheumatoid arthritis (RA).
Sinomenine (SIN) is an effective immunosuppressive and anti-inflammatory drug used for …

Activated fibroblast-like synovial (FLS) cells are regarded as an important target for
rheumatoid arthritis (RA) treatment via starvation therapy mediated by glucose oxidase …

Tissue macrophages (Mϕ) are essential effector cells in rheumatoid arthritis (RA),
contributing to autoimmune tissue inflammation through diverse effector functions. Their …

Macrophages are innate immune cells in the organism and can be found in almost tissues
and organs. They are highly plastic and heterogeneous cells and can participate in the …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with M1-type
macrophage activation. Mesenchymal stem cells (MSCs) therapies have shown promise in …

Inflammatory infiltration and bone destruction are important pathological features of
rheumatoid arthritis (RA), which originate from the disturbed niche of macrophages. Here …