Enzymes' power for plastics degradation

V Tournier, S Duquesne, F Guillamot… - Chemical …, 2023 - ACS Publications
Plastics are everywhere in our modern way of living, and their production keeps increasing
every year, causing major environmental concerns. Nowadays, the end-of-life management …

Expanding plastics recycling technologies: chemical aspects, technology status and challenges

H Li, HA Aguirre-Villegas, RD Allen, X Bai… - Green …, 2022 - pubs.rsc.org
Less than 10% of the plastics generated globally are recycled, while the rest are incinerated,
accumulated in landfills, or leak into the environment. New technologies are emerging to …

Directed evolution of an efficient and thermostable PET depolymerase

EL Bell, R Smithson, S Kilbride, J Foster, FJ Hardy… - Nature Catalysis, 2022 - nature.com
The recent discovery of Is PETase, a hydrolytic enzyme that can deconstruct poly (ethylene
terephthalate)(PET), has sparked great interest in biocatalytic approaches to recycle …

Sourcing thermotolerant poly (ethylene terephthalate) hydrolase scaffolds from natural diversity

E Erickson, JE Gado, L Avilán, F Bratti… - Nature …, 2022 - nature.com
Enzymatic deconstruction of poly (ethylene terephthalate)(PET) is under intense
investigation, given the ability of hydrolase enzymes to depolymerize PET to its constituent …

Mechanism-based design of efficient PET hydrolases

R Wei, G von Haugwitz, L Pfaff, J Mican… - ACS …, 2022 - ACS Publications
Polyethylene terephthalate (PET) is the most widespread synthetic polyester, having been
utilized in textile fibers and packaging materials for beverages and food, contributing …

Multiple substrate binding mode-guided engineering of a thermophilic PET hydrolase

L Pfaff, J Gao, Z Li, A Jäckering, G Weber… - ACS …, 2022 - ACS Publications
Thermophilic polyester hydrolases (PES-H) have recently enabled biocatalytic recycling of
the mass-produced synthetic polyester polyethylene terephthalate (PET), which has found …

Particle size reduction of poly (ethylene terephthalate) increases the rate of enzymatic depolymerization but does not increase the overall conversion extent

RK Brizendine, E Erickson, SJ Haugen… - ACS Sustainable …, 2022 - ACS Publications
Enzymatic depolymerization of poly (ethylene terephthalate)(PET) has emerged as a
potential method for PET recycling, but extensive thermomechanical preprocessing to …

A versatile microbial platform as a tunable whole-cell chemical sensor

JM Hernández-Sancho, A Boudigou… - Nature …, 2024 - nature.com
Biosensors are used to detect and quantify chemicals produced in industrial microbiology
with high specificity, sensitivity, and portability. Most biosensors, however, are limited by the …

Computational redesign of a hydrolase for nearly complete PET depolymerization at industrially relevant high-solids loading

Y Cui, Y Chen, J Sun, T Zhu, H Pang, C Li… - Nature …, 2024 - nature.com
Biotechnological plastic recycling has emerged as a suitable option for addressing the
pollution crisis. A major breakthrough in the biodegradation of poly (ethylene …

Conformational selection in biocatalytic plastic degradation by PETase

B Guo, SR Vanga, X Lopez-Lorenzo… - Acs …, 2022 - ACS Publications
Due to the steric effects imposed by bulky polymers, the formation of catalytically competent
enzyme and substrate conformations is critical in the biodegradation of plastics. In poly …