NF-kB: a crucial transcription factor for glial and neuronal cell function

LAJ O'Neill, C Kaltschmidt - Trends in neurosciences, 1997‏ - cell.com
Transcription factors provide the link between early membrane-proximal signalling events
and changes in gene expression. NF-kB is one of the best-characterized transcription …

Astrocytes and microglia and their potential link with autism spectrum disorders

F Petrelli, L Pucci, P Bezzi - Frontiers in cellular neuroscience, 2016‏ - frontiersin.org
The cellular mechanism (s) underlying autism spectrum disorders (ASDs) are not fully
understood although it has been shown that various genetic and environmental factors …

Constitutive NF-kB activity in neurons

C Kaltschmidt, B Kaltschmidt, H Neumann… - … and cellular biology, 1994‏ - Taylor & Francis
NF-kB is an inducible transcription factor present in many cell types in a latent cytoplasmic
form. So far, only immune cells including mature B cells, thymocytes, and adherent …

Transcription factor nuclear factor-kappa B is activated in neurons after focal cerebral ischemia

D Stephenson, T Yin, EB Smalstig… - Journal of Cerebral …, 2000‏ - journals.sagepub.com
Nuclear factor-kappa B (NF-kB) is a multisubunit transcription factor that when activated
induces the expression of genes encoding acute-phase proteins, cell adhesion molecules …

Stimulation of ionotropic glutamate receptors activates transcription factor NF-kappa B in primary neurons.

C Kaltschmidt, B Kaltschmidt, PA Baeuerle - Proceedings of the National …, 1995‏ - pnas.org
L-Glutamate is the most common excitatory neurotransmitter in the brain and plays a crucial
role in neuronal plasticity as well as in neurotoxicity. While a large body of literature …

The role of the interleukin-1 family in complications of prematurity

EA Green, SP Garrick, B Peterson, PJ Berger… - International Journal of …, 2023‏ - mdpi.com
Preterm birth is a major contributor to neonatal morbidity and mortality. Complications of
prematurity such as bronchopulmonary dysplasia (BPD, affecting the lung), pulmonary …

Temporal patterns of the cerebral inflammatory response in the rat lithium–pilocarpine model of temporal lobe epilepsy

B Voutsinos-Porche, E Koning, H Kaplan… - Neurobiology of …, 2004‏ - Elsevier
To better understand the role of inflammatory responses in temporal lobe epilepsy, we
characterized Interleukin1-β (IL1-β), Nuclear Factor-κB (NF-κB), and Cyclooxygenase-2 …

Expression and regulation of interleukin-1 receptors in the brain. Role in cytokines-induced sickness behavior

P Parnet, KW Kelley, RM Bluthé, R Dantzer - Journal of neuroimmunology, 2002‏ - Elsevier
Sickness behavior refers to the coordinated set of behavior changes that develop in sick
individuals during the course of an infection. At the molecular level, these changes are due …

Neuronal death and survival in two models of hypoxic-ischemic brain damage

M Walton, B Connor, P Lawlor, D Young… - Brain research …, 1999‏ - Elsevier
Two unilateral hypoxic-ischemia (HI) models (moderate and severe) in immature rat brain
have been used to investigate the role of various transcription factors and related proteins in …

Estrogen attenuates nuclear factor-kappa B activation induced by transient cerebral ischemia

Y Wen, S Yang, R Liu, E Perez, KD Yi, P Koulen… - Brain research, 2004‏ - Elsevier
The protective effects of estrogens have been widely reported in a number of animal and cell
culture models, but the molecular mechanisms of this potent neuroprotective activity are not …