Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests

M Masoodi, A Gastaldelli, T Hyötyläinen… - Nature reviews …, 2021 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases
worldwide and is often associated with aspects of metabolic syndrome. Despite its …

Noninvasive assessment of liver disease in patients with nonalcoholic fatty liver disease

L Castera, M Friedrich-Rust, R Loomba - Gastroenterology, 2019 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is estimated to afflict approximately 1 billion
individuals worldwide. In a subset of NAFLD patients, who have the progressive form of …

Metabolic liver disease in diabetes–from mechanisms to clinical trials

B Dewidar, S Kahl, K Pafili, M Roden - Metabolism, 2020 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) comprises fatty liver (steatosis), non-alcoholic
steatohepatitis (NASH) and fibrosis/cirrhosis and may lead to end-stage liver failure or …

Performance of plasma biomarkers and diagnostic panels for nonalcoholic steatohepatitis and advanced fibrosis in patients with type 2 diabetes

F Bril, MJ McPhaul, MP Caulfield, VC Clark… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE The 2019 Standards of Medical Care in Diabetes suggested that patients with
nonalcoholic fatty liver disease (NAFLD) should be evaluated for liver fibrosis. However, the …

Economic and clinical burden of nonalcoholic steatohepatitis in patients with type 2 diabetes in the US

ZM Younossi, RP Tampi, A Racila, Y Qiu… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE Nonalcoholic steatohepatitis (NASH) is a progressive form of nonalcoholic fatty
liver disease (NAFLD) and is strongly associated with type 2 diabetes mellitus (T2DM) …

The role of omics in the pathophysiology, diagnosis and treatment of non-alcoholic fatty liver disease

N Perakakis, K Stefanakis, CS Mantzoros - Metabolism, 2020 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a multifaceted metabolic disorder, whose
spectrum covers clinical, histological and pathophysiological developments ranging from …

Diagnostic modalities of non-alcoholic fatty liver disease: from biochemical biomarkers to multi-omics non-invasive approaches

E Martinou, M Pericleous, I Stefanova, V Kaur… - Diagnostics, 2022 - mdpi.com
Non-Alcoholic Fatty Liver Disease (NAFLD) is currently the most common cause of chronic
liver disease worldwide, and its prevalence is increasing globally. NAFLD is a multifaceted …

[HTML][HTML] Recent advances in nonalcoholic fatty liver disease metabolomics

HY Kim - Clinical and molecular hepatology, 2021 - ncbi.nlm.nih.gov
The clinical phenotypes of nonalcoholic fatty liver disease (NAFLD) encompass from simple
steatosis to nonalcoholic steatohepatitis (NASH) with varying degrees of fibrosis or cirrhosis …

Untargeted metabolomics as a diagnostic tool in NAFLD: discrimination of steatosis, steatohepatitis and cirrhosis

M Masarone, J Troisi, A Aglitti, P Torre, A Colucci… - Metabolomics, 2021 - Springer
Abstract Introduction Non-Alcoholic Fatty Liver Disease encompasses a spectrum of
diseases ranging from simple steatosis to steatohepatitis (or NASH), up to cirrhosis and …

Performance of the SteatoTest, ActiTest, NashTest and FibroTest in a multiethnic cohort of patients with type 2 diabetes mellitus

F Bril, MJ McPhaul, MP Caulfield… - Journal of …, 2019 - journals.sagepub.com
Fibromax is a diagnostic tool composed of the combination of 4 non-invasive biomarker
panels for the diagnosis of steatosis (SteatoTest), necrosis and inflammation (ActiTest and …