[HTML][HTML] The current science of sequence-defined macromolecules

K Hakobyan, BB Noble, J Xu - Progress in Polymer Science, 2023 - Elsevier
A fundamental endeavour in macromolecular science is the control of molecular-level
complexity, including molecular weight distribution, end groups and architecture. Since the …

Differential Peptide Multi‐Macrocyclizations at the Surface of a Helical Foldamer Template

S Dengler, C Douat, I Huc - Angewandte Chemie International …, 2022 - Wiley Online Library
Hybrid sequences comprising a peptide with several Cys residues and an aromatic foldamer
helix with several chloroacetamide functions at its surface were synthesized. Such products …

An abiotic, tetrameric, eight-helix bundle

FS Menke, B Wicher, L Allmendinger, V Maurizot… - Chemical …, 2023 - pubs.rsc.org
Four helically folded aromatic oligoamide sequences containing either a chiral monomer
based on 2-(2-aminophenoxy)-propionic acid, an N-terminal (1H)-camphanyl group, or both …

Oligoarginine-conjugated peptide foldamers inhibiting vitamin D receptor-mediated transcription

M Takyo, Y Sato, N Hirata, K Tsuchiya, H Ishida… - ACS …, 2022 - ACS Publications
The vitamin D receptor (VDR) is a nuclear receptor, which is involved in several
physiological processes, including differentiation and bone homeostasis. The VDR is a …

Supramolecular helix of an oligomeric azapeptide building block containing four β-turn structures

Y Zhao, X Yan, YB Jiang - Chemical Communications, 2024 - pubs.rsc.org
Oligomers of benzoylalanine-based amidothioureas containing four β-turn structures spaced
by meta-substituted benzenes were shown to undergo assembly in dilute CH3CN solution …

Microwave-assisted synthesis of peptidomimetic trans-delta-aminopent-3-enoic acid and its derivatives

K Saranraj, KMP Raja - New Journal of Chemistry, 2024 - pubs.rsc.org
An environmentally friendly solution-phase synthesis has been developed for producing
trans-5-aminopenta-3-enoic acid (trans-δ-Apa), along with several Nα-and C-terminal …

Herringbone Helical Foldamers from Aromatic Ether Derived ϵ‐Amino Acid Peptides

Y Yang, M Xue - Chemistry–A European Journal, 2023 - Wiley Online Library
Oligomers based on an aromatic ether derived ϵ‐amino acid peptides folded into
herringbone helical structures, induced by successive NH− O− NH & O− NH− O bifurcated …

Structure, Conformation and Contact Analyses of Six Aromatic Diamide Diesters

IA Osman, V McKee, C Jelsch, JF Gallagher - Crystals, 2023 - mdpi.com
Six meta-substituted isophthalamide diesters (DxE) and pyridinedicarboxamides (PxE) are
reported with spectroscopic and crystal structure analyses (D= meta-C6H4; P= meta …

Differenzierte Peptid‐Multi‐Makrozyklisierungen an der Oberfläche eines helikalen Foldamer‐Templats

S Dengler, C Douat, I Huc - Angewandte Chemie, 2022 - Wiley Online Library
Es wurden hybride Sequenzen synthetisiert, die Peptide mit einer Reihe von Cystein‐
Resten und aromatische Foldamer‐Helices mit mehreren Chloracetamid‐Funktionen an …