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Cancer biomarkers: emerging trends and clinical implications for personalized treatment
The integration of cancer biomarkers into oncology has revolutionized cancer treatment,
yielding remarkable advancements in cancer therapeutics and the prognosis of cancer …
yielding remarkable advancements in cancer therapeutics and the prognosis of cancer …
[HTML][HTML] Liquid biopsy for advanced NSCLC: a consensus statement from the international association for the study of lung cancer
Although precision medicine has had a mixed impact on the clinical management of patients
with advanced-stage cancer overall, for NSCLC, and more specifically for lung …
with advanced-stage cancer overall, for NSCLC, and more specifically for lung …
Non-viral precision T cell receptor replacement for personalized cell therapy
T cell receptors (TCRs) enable T cells to specifically recognize mutations in cancer cells,–.
Here we developed a clinical-grade approach based on CRISPR–Cas9 non-viral precision …
Here we developed a clinical-grade approach based on CRISPR–Cas9 non-viral precision …
[HTML][HTML] ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group
Circulating tumour DNA (ctDNA) assays conducted on plasma are rapidly develo** a
strong evidence base for use in patients with cancer. The European Society for Medical …
strong evidence base for use in patients with cancer. The European Society for Medical …
A shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results
AR Rappaport, C Kyi, M Lane, MG Hart, ML Johnson… - Nature medicine, 2024 - nature.com
Therapeutic vaccines that elicit cytotoxic T cell responses targeting tumor-specific
neoantigens hold promise for providing long-term clinical benefit to patients with cancer …
neoantigens hold promise for providing long-term clinical benefit to patients with cancer …
ctDNA guiding adjuvant immunotherapy in urothelial carcinoma
Minimally invasive approaches to detect residual disease after surgery are needed to
identify patients with cancer who are at risk for metastatic relapse. Circulating tumour DNA …
identify patients with cancer who are at risk for metastatic relapse. Circulating tumour DNA …
Detection and characterization of lung cancer using cell-free DNA fragmentomes
D Mathios, JS Johansen, S Cristiano, JE Medina… - Nature …, 2021 - nature.com
Non-invasive approaches for cell-free DNA (cfDNA) assessment provide an opportunity for
cancer detection and intervention. Here, we use a machine learning model for detecting …
cancer detection and intervention. Here, we use a machine learning model for detecting …
Using circulating tumor DNA in colorectal cancer: current and evolving practices
There exists a tremendous opportunity in identifying and determining the appropriate
predictive and prognostic biomarker (s) for risk stratification of patients with colorectal …
predictive and prognostic biomarker (s) for risk stratification of patients with colorectal …
Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment
AJ Widman, M Shah, A Frydendahl, D Halmos… - Nature medicine, 2024 - nature.com
In solid tumor oncology, circulating tumor DNA (ctDNA) is poised to transform care through
accurate assessment of minimal residual disease (MRD) and therapeutic response …
accurate assessment of minimal residual disease (MRD) and therapeutic response …
Practical recommendations for using ctDNA in clinical decision making
SA Cohen, MC Liu, A Aleshin - Nature, 2023 - nature.com
The continuous improvement in cancer care over the past decade has led to a gradual
decrease in cancer-related deaths. This is largely attributed to improved treatment and …
decrease in cancer-related deaths. This is largely attributed to improved treatment and …