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Nanoparticle protein corona: from structure and function to therapeutic targeting
Nanoparticle (NP)-based therapeutics have ushered in a new era in translational medicine.
However, despite the clinical success of NP technology, it is not well-understood how NPs …
However, despite the clinical success of NP technology, it is not well-understood how NPs …
Drug delivery across the blood–brain barrier: recent advances in the use of nanocarriers
The blood–brain barrier (BBB) has a significant contribution to homeostasis and protection
of the CNS. However, it also limits the crossing of therapeutics and thereby complicates the …
of the CNS. However, it also limits the crossing of therapeutics and thereby complicates the …
Current approaches for the exploration of antimicrobial activities of nanoparticles
Infectious diseases of bacterial and viral origins contribute to substantial mortality worldwide.
Collaborative efforts have been underway between academia and the industry to develop …
Collaborative efforts have been underway between academia and the industry to develop …
Enzyme immobilization onto the nanomaterials: Application in enzyme stability and prodrug-activated cancer therapy
Nanoparticles (NPs) have been widely used for immobilization of wide ranges of enzymes.
However, the stabilization of enzymes on NPs is a major challenge, crucial for regulating …
However, the stabilization of enzymes on NPs is a major challenge, crucial for regulating …
Interactions between nanoparticle-based food additives and other food ingredients: A review of current knowledge
Background Nanomaterials are being explored in the food and agricultural industries for
their potential applications in improving the safety, quality, health, and sustainability of the …
their potential applications in improving the safety, quality, health, and sustainability of the …
Biofluid specific protein coronas affect lipid nanoparticle behavior in vitro
D van Straten, H Sork, L van de Schepop… - Journal of Controlled …, 2024 - Elsevier
Lipid nanoparticles (LNPs) have successfully entered the clinic for the delivery of mRNA-and
siRNA-based therapeutics, most recently as vaccines for COVID-19. Nevertheless, there is a …
siRNA-based therapeutics, most recently as vaccines for COVID-19. Nevertheless, there is a …
Explaining chemical clues of metal organic framework-nanozyme nano-/micro-motors in targeted treatment of cancers: benchmarks and challenges
Abstract Nowadays, nano-/micro-motors are considered as powerful tools in different areas
ranging from cleaning all types of contaminants, to development of Targeted drug delivery …
ranging from cleaning all types of contaminants, to development of Targeted drug delivery …
The role of apolipoprotein-and vitronectin-enriched protein corona on lipid nanoparticles for in vivo targeted delivery and transfection of oligonucleotides in murine …
The application of lipid-based nanoparticle (LNP) delivery systems remains a popular
strategy for the systemic delivery of gene therapies to specific disease targets, including …
strategy for the systemic delivery of gene therapies to specific disease targets, including …
Assessing the in vitro toxicity of airborne (nano)particles to the human respiratory system: from basic to advanced models
MJ Bessa, F Brandão, F Rosário, L Moreira… - Journal of Toxicology …, 2023 - Taylor & Francis
Several studies have been conducted to address the potential adverse health risks
attributed to exposure to nanoscale materials. While in vivo studies are fundamental for …
attributed to exposure to nanoscale materials. While in vivo studies are fundamental for …
[HTML][HTML] Understanding protein-nanoparticle interactions leading to protein corona formation: In vitro-in vivo correlation study
Nanoparticles (NPs) in contact with biological fluids form a biomolecular corona through
interactions with proteins, lipids, and sugars, acquiring new physicochemical properties …
interactions with proteins, lipids, and sugars, acquiring new physicochemical properties …