Nanoparticle protein corona: from structure and function to therapeutic targeting

G Bashiri, MS Padilla, KL Swingle, SJ Shepherd… - Lab on a Chip, 2023 - pubs.rsc.org
Nanoparticle (NP)-based therapeutics have ushered in a new era in translational medicine.
However, despite the clinical success of NP technology, it is not well-understood how NPs …

Drug delivery across the blood–brain barrier: recent advances in the use of nanocarriers

JJE Mulvihill, EM Cunnane, AM Ross, JT Duskey… - …, 2020 - Taylor & Francis
The blood–brain barrier (BBB) has a significant contribution to homeostasis and protection
of the CNS. However, it also limits the crossing of therapeutics and thereby complicates the …

Current approaches for the exploration of antimicrobial activities of nanoparticles

NA Rosli, YH Teow, E Mahmoudi - Science and technology of …, 2021 - Taylor & Francis
Infectious diseases of bacterial and viral origins contribute to substantial mortality worldwide.
Collaborative efforts have been underway between academia and the industry to develop …

Enzyme immobilization onto the nanomaterials: Application in enzyme stability and prodrug-activated cancer therapy

M Sharifi, MJ Sohrabi, SH Hosseinali, A Hasan… - International Journal of …, 2020 - Elsevier
Nanoparticles (NPs) have been widely used for immobilization of wide ranges of enzymes.
However, the stabilization of enzymes on NPs is a major challenge, crucial for regulating …

Interactions between nanoparticle-based food additives and other food ingredients: A review of current knowledge

M Moradi, R Razavi, AK Omer, A Farhangfar… - Trends in food science & …, 2022 - Elsevier
Background Nanomaterials are being explored in the food and agricultural industries for
their potential applications in improving the safety, quality, health, and sustainability of the …

Biofluid specific protein coronas affect lipid nanoparticle behavior in vitro

D van Straten, H Sork, L van de Schepop… - Journal of Controlled …, 2024 - Elsevier
Lipid nanoparticles (LNPs) have successfully entered the clinic for the delivery of mRNA-and
siRNA-based therapeutics, most recently as vaccines for COVID-19. Nevertheless, there is a …

Explaining chemical clues of metal organic framework-nanozyme nano-/micro-motors in targeted treatment of cancers: benchmarks and challenges

M Falahati, M Sharifi, TLMT Hagen - Journal of Nanobiotechnology, 2022 - Springer
Abstract Nowadays, nano-/micro-motors are considered as powerful tools in different areas
ranging from cleaning all types of contaminants, to development of Targeted drug delivery …

The role of apolipoprotein-and vitronectin-enriched protein corona on lipid nanoparticles for in vivo targeted delivery and transfection of oligonucleotides in murine …

D Chen, N Parayath, S Ganesh, W Wang, M Amiji - Nanoscale, 2019 - pubs.rsc.org
The application of lipid-based nanoparticle (LNP) delivery systems remains a popular
strategy for the systemic delivery of gene therapies to specific disease targets, including …

Assessing the in vitro toxicity of airborne (nano)particles to the human respiratory system: from basic to advanced models

MJ Bessa, F Brandão, F Rosário, L Moreira… - Journal of Toxicology …, 2023 - Taylor & Francis
Several studies have been conducted to address the potential adverse health risks
attributed to exposure to nanoscale materials. While in vivo studies are fundamental for …

[HTML][HTML] Understanding protein-nanoparticle interactions leading to protein corona formation: In vitro-in vivo correlation study

C Marques, P Maroni, L Maurizi, O Jordan… - International Journal of …, 2024 - Elsevier
Nanoparticles (NPs) in contact with biological fluids form a biomolecular corona through
interactions with proteins, lipids, and sugars, acquiring new physicochemical properties …