Whipworm and roundworm infections

KJ Else, J Keiser, CV Holland, RK Grencis… - Nature Reviews …, 2020 - nature.com
Trichuriasis and ascariasis are neglected tropical diseases caused by the gastrointestinal
dwelling nematodes Trichuris trichiura (a whipworm) and Ascaris lumbricoides (a …

Recent advances in type-2-cell-mediated immunity: insights from helminth infection

NL Harris - Immunity, 2017 - cell.com
Type-2-cell-mediated immune responses play a critical role in mediating both host-
resistance and disease-tolerance mechanisms during helminth infections. Recently, type 2 …

The porcine innate immune system: an update

KH Mair, C Sedlak, T Käser, A Pasternak… - Developmental & …, 2014 - Elsevier
Over the last few years, we have seen an increasing interest and demand for pigs in
biomedical research. Domestic pigs (Sus scrofa domesticus) are closely related to humans …

First responders: innate immunity to helminths

JM Inclan-Rico, MC Siracusa - Trends in parasitology, 2018 - cell.com
Helminth infections represent a significant public health concern resulting in devastating
morbidity and economic consequences across the globe. Helminths migrate through …

A polyphenol-enriched diet and Ascaris suum infection modulate mucosal immune responses and gut microbiota composition in pigs

AR Williams, L Krych, H Fauzan Ahmad, P Nejsum… - PLoS one, 2017 - journals.plos.org
Polyphenols are a class of bioactive plant secondary metabolites that are thought to have
beneficial effects on gut health, such as modulation of mucosal immune and inflammatory …

Anthelmintic activity of trans-cinnamaldehyde and A- and B-type proanthocyanidins derived from cinnamon (Cinnamomum verum)

AR Williams, A Ramsay, TVA Hansen, HM Ropiak… - Scientific Reports, 2015 - nature.com
Cinnamon (Cinnamomum verum) has been shown to have anti-inflammatory and
antimicrobial properties, but effects on parasitic worms of the intestine have not been …

Th2-biased immune responses to body migrating Ascaris larvae in primary infection are associated with pathology but not protection

LE Elizalde-Velázquez, J Schlosser-Brandenburg… - Scientific Reports, 2024 - nature.com
Helminth infections lead to an overdispersion of the parasites in humans as well as in
animals. We asked whether early immune responses against migrating Ascaris larvae are …

The framework for human host immune responses to four types of parasitic infections and relevant key JAK/STAT signaling

TH Wen, KW Tsai, YJ Wu, MT Liao, KC Lu… - International Journal of …, 2021 - mdpi.com
The human host immune responses to parasitic infections are complex. They can be
categorized into four immunological pathways mounted against four types of parasitic …

In silico design of a polypeptide as a vaccine candidate against ascariasis

FMD Evangelista, AHM van Vliet, SP Lawton… - Scientific reports, 2023 - nature.com
Ascariasis is the most prevalent zoonotic helminthic disease worldwide, and is responsible
for nutritional deficiencies, particularly hindering the physical and neurological development …

Dietary fiber sources and non-starch polysaccharide-degrading enzymes modify mucin expression and the immune profile of the swine ileum

M Ferrandis Vila, MP Trudeau, YT Hung, Z Zeng… - PLoS …, 2018 - journals.plos.org
Due to their complex chemical and physical properties, the effects and mechanisms of action
of natural sources of dietary fiber on the intestine are unclear. Pigs are commonly fed high …