Microcircuits for spatial coding in the medial entorhinal cortex

JJ Tukker, P Beed, M Brecht, R Kempter… - Physiological …, 2022 - journals.physiology.org
The hippocampal formation is critically involved in learning and memory and contains a
large proportion of neurons encoding aspects of the organism's spatial surroundings. In the …

The grid code for ordered experience

JW Rueckemann, M Sosa, LM Giocomo… - Nature Reviews …, 2021 - nature.com
Entorhinal cortical grid cells fire in a periodic pattern that tiles space, which is suggestive of a
spatial coordinate system. However, irregularities in the grid pattern as well as responses of …

Generation of stable heading representations in diverse visual scenes

SS Kim, AM Hermundstad, S Romani, LF Abbott… - Nature, 2019 - nature.com
Many animals rely on an internal heading representation when navigating in varied
environments,,,,,,,,–. How this representation is linked to the sensory cues that define …

Sensorimotor experience remaps visual input to a heading-direction network

YE Fisher, J Lu, I D'Alessandro, RI Wilson - Nature, 2019 - nature.com
In the Drosophila brain,'compass' neurons track the orientation of the body and head (the
fly's heading) during navigation,. In the absence of visual cues, the compass neuron network …

[HTML][HTML] Population dynamics of head-direction neurons during drift and reorientation

Z Ajabi, AT Keinath, XX Wei, MP Brandon - Nature, 2023 - nature.com
The head direction (HD) system functions as the brain's internal compass,, classically
formalized as a one-dimensional ring attractor network,. In contrast to a globally consistent …

Principles governing the integration of landmark and self-motion cues in entorhinal cortical codes for navigation

MG Campbell, SA Ocko, CS Mallory, IIC Low… - Nature …, 2018 - nature.com
To guide navigation, the nervous system integrates multisensory self-motion and landmark
information. We dissected how these inputs generate spatial representations by recording …

The neuroanatomical ultrastructure and function of a biological ring attractor

DB Turner-Evans, KT Jensen, S Ali, T Paterson… - Neuron, 2020 - cell.com
Neural representations of head direction (HD) have been discovered in many species.
Theoretical work has proposed that the dynamics associated with these representations are …

A unified theory for the computational and mechanistic origins of grid cells

B Sorscher, GC Mel, SA Ocko, LM Giocomo, S Ganguli - Neuron, 2023 - cell.com
The discovery of entorhinal grid cells has generated considerable interest in how and why
hexagonal firing fields might emerge in a generic manner from neural circuits, and what their …

Flexible modulation of sequence generation in the entorhinal–hippocampal system

DC McNamee, KL Stachenfeld, MM Botvinick… - Nature …, 2021 - nature.com
Exploration, consolidation and planning depend on the generation of sequential state
representations. However, these algorithms require disparate forms of sampling dynamics …

Transforming a head direction signal into a goal-oriented steering command

EA Westeinde, E Kellogg, PM Dawson, J Lu… - Nature, 2024 - nature.com
To navigate, we must continuously estimate the direction we are headed in, and we must
correct deviations from our goal. Direction estimation is accomplished by ring attractor …