Immunoinformatics-aided design of a peptide based multiepitope vaccine targeting glycoproteins and membrane proteins against monkeypox virus
Monkeypox is a self-limiting zoonotic viral disease and causes smallpox-like symptoms. The
disease has a case fatality ratio of 3–6% and, recently, a multi-country outbreak of the …
disease has a case fatality ratio of 3–6% and, recently, a multi-country outbreak of the …
Secreted Aspartyl Proteinases Targeted Multi-Epitope Vaccine Design for Candida dubliniensis Using Immunoinformatics
Candida dubliniensis is an opportunistic pathogen associated with oral and invasive fungal
infections in immune-compromised individuals. Furthermore, the emergence of C …
infections in immune-compromised individuals. Furthermore, the emergence of C …
Immunoinformatics-Aided Design and In Vivo Validation of a Peptide-Based Multiepitope Vaccine Targeting Canine Circovirus
Canine circovirus (CanineCV) is a deadly pathogen affecting both domestic and wild
carnivores including dogs. No vaccine against CanineCV is available commercially or under …
carnivores including dogs. No vaccine against CanineCV is available commercially or under …
In silico design of a broad-spectrum multiepitope vaccine against influenza virus
L Yuan, X Li, M Li, R Bi, Y Li, J Song, W Li… - International Journal of …, 2024 - Elsevier
Influenza remains a global health concern due to its potential to cause pandemics as a
result of rapidly mutating influenza virus strains. Existing vaccines often struggle to keep up …
result of rapidly mutating influenza virus strains. Existing vaccines often struggle to keep up …
Dengue vaccination: towards a new dawn of curbing dengue infection
Dengue is an infectious disease caused by dengue virus (DENV) and is a serious global
burden. Antibody-dependent enhancement and the ability of DENV to infect immune cells …
burden. Antibody-dependent enhancement and the ability of DENV to infect immune cells …
Immunoinformatics-aided rational design of a multi-epitope vaccine targeting feline infectious peritonitis virus
Feline infectious peritonitis (FIP) is a grave and frequently lethal ailment instigated by feline
coronavirus (FCoV) in wild and domestic feline species. The spike (S) protein of FCoV …
coronavirus (FCoV) in wild and domestic feline species. The spike (S) protein of FCoV …
Deciphering the immunogenicity of monkeypox proteins for designing the potential mRNA vaccine
The Monkeypox virus (MPXV), an orthopox virus, is responsible for monkeypox in humans, a
zoonotic disease similar to smallpox. This infection first appeared in the 1970s in humans …
zoonotic disease similar to smallpox. This infection first appeared in the 1970s in humans …
Toward α‐1, 3/4 fucosyltransferases targeted drug discovery: In silico uncovering of promising natural inhibitors of fucosyltransferase 6
JSL Magdaleno, RK Grewal… - Journal of Cellular …, 2023 - Wiley Online Library
Abstract Sialyl Lewis X (sLex) antigen is a fucosylated cell‐surface glycan that is normally
involved in cell‐cell interactions. The enhanced expression of sLex on cell surface glycans …
involved in cell‐cell interactions. The enhanced expression of sLex on cell surface glycans …
Immunoinformatics and computational approaches driven designing a novel vaccine candidate against Powassan virus
TL Nguyen, H Kim - Scientific Reports, 2024 - nature.com
Powassan virus (POWV) is an arthropod-borne virus (arbovirus) capable of causing severe
illness in humans for severe neurological complications, and its incidence has been on the …
illness in humans for severe neurological complications, and its incidence has been on the …
Epitope-based Vaccine development: A detailed overview from in-silico vaccine design to wet lab validation
In-silico epitope-based vaccine is the cornerstone of modern vaccine development and is
illuminating by a growing number of experimental and computational methods. The reverse …
illuminating by a growing number of experimental and computational methods. The reverse …